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Literature DB >> 7335

Blockade by burimamide of the restorative effect of histamine in tetrodotoxin-treated heart preparations.

Abstract

1 In isolated heart preparations in which fast sodium channels were blocked by tetrodotoxin (2-4 x 10(-5) M), excitability was restored by histamine (6 x 10(-6) M to 10(-5) M). 2 This effect was antagonized by EDTA (2 X 10(-6) M),D600 compound (0.5mug/ml) and the H2-receptor antagonist, burimamide(2 X 10(-4) M).

Entities: Chemical

Mesh：

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Year: 1976 PMID： 7335 PMCID： PMC1667117 DOI： 10.1111/j.1476-5381.1976.tb07474.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

6 in total

1. Definition and antagonism of histamine H 2 -receptors.

Authors: J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal: Nature Date: 1972-04-21 Impact factor: 49.962

2. Histamine effects on cardiac contractility, phosphorylase and adenyl cyclase.

Authors: J H McNeill; L D Muschek
Journal: J Mol Cell Cardiol Date: 1972-12 Impact factor: 5.000

3. Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors.

Authors: M Kohlhardt; B Bauer; H Krause; A Fleckenstein
Journal: Pflugers Arch Date: 1972 Impact factor: 3.657

4. Restoration effects of histamine on action potential in potassium-depolarized guinea-pig papillary muscle.

Authors: S Houki
Journal: Arch Int Pharmacodyn Ther Date: 1973-11

5. Blockade by burimamide of the effects of histamine and histamine analogs on cardiac contractility, phosphorylase activation and cyclic adenosine monophosphate.

Authors: J H McNeill; S C Verma
Journal: J Pharmacol Exp Ther Date: 1974-01 Impact factor: 4.030

6. Effects of histamine and noradrenaline on contractile force of guinea-pig ventricular strips: antagonism by burimamide and metiamide.

Authors: F Moroni; F Ledda; R Fantozzi; A Mugelli; P F Mannaioni
Journal: Agents Actions Date: 1974-12

6 in total

9 in total

1. A histamine-induced decrease of action potential duration in cardiac muscle mediated by the H2 receptors.

Authors: F Ledda; A Mugelli; L Mantelli
Journal: Agents Actions Date: 1977-07

2. Effects of H1- and H2-receptor antagonists on calcium-dependent action potentials produced by histamine in rabbit left auricles depolarized by potassium.

Authors: V Kecskeméti
Journal: Agents Actions Date: 1981-04

3. Calcium antagonistic and antiarrhythmic actions of CPU-23, a substituted tetrahydroisoquinoline.

Authors: H Dong; J Z Sheng; C M Lee; T M Wong
Journal: Br J Pharmacol Date: 1993-05 Impact factor: 8.739

4. Some characteristics of the inotropic effects of histamine H1- and H2-receptor agonists in comparison with those of alpha- and beta-adrenoceptor agonists.

Authors: L Mantelli; S Amerini; A Picchi; A Mugelli; F Ledda
Journal: Agents Actions Date: 1982-04

Blockade by burimamide of the restorative effect of histamine in tetrodotoxin-treated heart preparations.

1. Definition and antagonism of histamine H 2 -receptors.

2. Histamine effects on cardiac contractility, phosphorylase and adenyl cyclase.

3. Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors.

4. Restoration effects of histamine on action potential in potassium-depolarized guinea-pig papillary muscle.

5. Blockade by burimamide of the effects of histamine and histamine analogs on cardiac contractility, phosphorylase activation and cyclic adenosine monophosphate.

6. Effects of histamine and noradrenaline on contractile force of guinea-pig ventricular strips: antagonism by burimamide and metiamide.

1. A histamine-induced decrease of action potential duration in cardiac muscle mediated by the H2 receptors.

2. Effects of H1- and H2-receptor antagonists on calcium-dependent action potentials produced by histamine in rabbit left auricles depolarized by potassium.

3. Calcium antagonistic and antiarrhythmic actions of CPU-23, a substituted tetrahydroisoquinoline.

4. Some characteristics of the inotropic effects of histamine H1- and H2-receptor agonists in comparison with those of alpha- and beta-adrenoceptor agonists.

5. Role of the oscillatory afterpotentials in the arrhythmogenic action of histamine.

6. Indirect evidence for a role of phosphatidylinositol turnover in the cardiac response to H1-receptor stimulation.

7. Histamine and abnormal automaticity in barium- and strophanthidin-treated sheep Purkinje fibers.

8. Dysrhythmias caused by histamine release in guinea pig and human hearts.

Review 9. Channel-mediated calcium current in the heart.