Literature DB >> 7334382

Hypoglycemic activity of polypeptide-p from a plant source.

P Khanna, S C Jain, A Panagariya, V P Dixit.   

Abstract

A hypoglycemic peptide, Polypeptide-p, has been isolated from fruit, seeds, and tissue of Momordica charantia Linn (bitter gourd). Amino acid analysis indicates a minimum molecular weight of approximately 11,000 (166 residues). Polypeptide-p is a very effective hypoglycemic agent when administered subcutaneously to gerbils, langurs, and humans.

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Year:  1981        PMID: 7334382     DOI: 10.1021/np50018a002

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  44 in total

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Review 3.  Prevention of non-enzymatic glycosylation (glycation): Implication in the treatment of diabetic complication.

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4.  Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats.

Authors:  Umesh C S Yadav; K Moorthy; Najma Z Baquer
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5.  Effect of bitter gourd (Momordica charantia) on glycaemic status in streptozotocin induced diabetic rats.

Authors:  A K Shetty; G Suresh Kumar; K Sambaiah; P V Salimath
Journal:  Plant Foods Hum Nutr       Date:  2005-09       Impact factor: 3.921

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7.  An overview of Indian novel traditional medicinal plants with anti-diabetic potentials.

Authors:  Rahul Gupta; Kumar Gaurav Bajpai; Samta Johri; A M Saxena
Journal:  Afr J Tradit Complement Altern Med       Date:  2007-10-27

Review 8.  Traditional chinese medicine in treatment of metabolic syndrome.

Authors:  Jun Yin; Hanjie Zhang; Jianping Ye
Journal:  Endocr Metab Immune Disord Drug Targets       Date:  2008-06       Impact factor: 2.895

9.  Expression and characterization of Momordica Chanrantia anti-hyperglycaemic peptide in Escherichia coli.

Authors:  Si-Xiu Liu; Zhong-Ping Fu; Rui-Min Mu; Zhi-Bi Hu; Fu-Jun Wang; Xiang-Rong Wang
Journal:  Mol Biol Rep       Date:  2009-07-08       Impact factor: 2.316

Review 10.  Nanotechnological approaches for the development of herbal drugs in treatment of diabetes mellitus - a critical review.

Authors:  Saritha Marella; Naga Venkata Krishna Vara Prasad Tollamadugu
Journal:  IET Nanobiotechnol       Date:  2018-08       Impact factor: 1.847

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