| Literature DB >> 7334186 |
M Smethurst, N P Bishun, D Fernandez, J Allen, J I Burn, J Alaghband-Zadeh, D C Williams.
Abstract
Cytosol and nuclear estrogen receptors and cytosol progesterone receptors were measured in 17 primary breast tumors and compared with sex chromatin frequencies. In cases with sex chromatin frequencies of greater than 20% there were 7/7 tumors with cytosol estrogen and progesterone receptors, 6/7 with cytosol and nuclear estrogen receptors, and 6/7 with all 3 receptors. This high proportion of receptor positive cases was not observed at lower sex chromatin frequencies. Sex chromatin frequencies in all the cytosol estrogen and progesterone receptor positive tumors were significantly higher (p less than 0.05) than in the other groups. Our results suggest a possible association between the presence of steroid hormone receptors and sex chromatin frequencies of greater than 20%.Entities:
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Year: 1981 PMID： 7334186 DOI： 10.1007/BF03348311
Source DB: PubMed Journal: J Endocrinol Invest ISSN： 0391-4097 Impact factor: 4.256