Literature DB >> 7331976

The Neonatal Narcotic Withdrawal Index: a device for the improvement of care in the abstinence syndrome.

M Green, F Suffet.   

Abstract

Management of 50 experimental newborn infants ill with narcotic withdrawal has been carried out with the aid of an instrument developed for measuring its severity, the Neonatal Narcotic Withdrawal Index (NNWI). With its use, infants exposed to methadone in utero have been successfully cared for with detoxification needed in less than 25% of cases and for durations of less than 2 weeks. The percentage of cases and the length of treatment is much less than is customary for infants who have been prenatally exposed to similar doses of methadone. Validity of the NNWI is shown by the statistically significant difference between the mean scores for experimental and control subjects, a high significant correlation between simultaneously measured scores by separate examiners, statistically significant correlations between subscores and total withdrawal scores for the narcotic-exposed experimental cases, and for this group, a statistically significant correlation between scores of withdrawal and the maternal dose of methadone. The simplicity of the NNWI should help to make it acceptable for use by physicians.

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Year:  1981        PMID: 7331976     DOI: 10.3109/00952998108999125

Source DB:  PubMed          Journal:  Am J Drug Alcohol Abuse        ISSN: 0095-2990            Impact factor:   3.829


  18 in total

1.  Methadone dosing strategies in preterm neonates can be simplified.

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Journal:  Br J Clin Pharmacol       Date:  2019-04-10       Impact factor: 4.335

Review 2.  Neonatal Adaptation Issues After Maternal Exposure to Prescription Drugs: Withdrawal Syndromes and Residual Pharmacological Effects.

Authors:  Irma Convertino; Alice Capogrosso Sansone; Alessandra Marino; Maria T Galiulo; Stefania Mantarro; Luca Antonioli; Matteo Fornai; Corrado Blandizzi; Marco Tuccori
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Review 3.  Current guidelines for the treatment of acute pain in children.

Authors:  V Bhatt-Mehta
Journal:  Drugs       Date:  1996-05       Impact factor: 9.546

4.  Consensus guidelines on sedation and analgesia in critically ill children.

Authors:  Stephen Playfor; Ian Jenkins; Carolyne Boyles; Imti Choonara; Gerald Davies; Tim Haywood; Gillian Hinson; Anton Mayer; Neil Morton; Tanya Ralph; Andrew Wolf
Journal:  Intensive Care Med       Date:  2006-05-13       Impact factor: 17.440

Review 5.  Pharmacologic management of the opioid neonatal abstinence syndrome.

Authors:  Walter K Kraft; John N van den Anker
Journal:  Pediatr Clin North Am       Date:  2012-08-30       Impact factor: 3.278

6.  Impact of a Standardized Treatment Guideline for Pediatric Iatrogenic Opioid Dependence: A Quality Improvement Initiative.

Authors:  Rima Abdouni; Teri Reyburn-Orne; Tarek H Youssef; Imad Y Haddad; Richard D Gerkin
Journal:  J Pediatr Pharmacol Ther       Date:  2016 Jan-Feb

Review 7.  The opioid-exposed newborn: assessment and pharmacologic management.

Authors:  Lauren M Jansson; Martha Velez; Cheryl Harrow
Journal:  J Opioid Manag       Date:  2009 Jan-Feb

8.  Current management of neonatal abstinence syndrome secondary to intrauterine opioid exposure.

Authors:  Jason R Wiles; Barbara Isemann; Laura P Ward; Alexander A Vinks; Henry Akinbi
Journal:  J Pediatr       Date:  2014-06-16       Impact factor: 4.406

9.  A randomised controlled trial of morphine versus phenobarbitone for neonatal abstinence syndrome.

Authors:  L Jackson; A Ting; S McKay; P Galea; C Skeoch
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2004-07       Impact factor: 5.747

Review 10.  Neonatal abstinence syndrome: essentials for the practitioner.

Authors:  Anita Siu; Christine A Robinson
Journal:  J Pediatr Pharmacol Ther       Date:  2014-07
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