Literature DB >> 7329203

Conversion of spironolactone to an active metabolite in target tissues: formation of 7 alpha-thiospironolactone by microsomal preparations from guinea pig liver, adrenals, kidneys, and testes.

J H Sherry, J P O'Donnell, H D Colby.   

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Year:  1981        PMID： 7329203     DOI： 10.1016/0024-3205(81)90532-4

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


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  1 in total

1.  Pharmacokinetics of canrenone and metabolites after base hydrolysis following single and multiple dose oral administration of spironolactone.

Authors:  P C Ho; D W Bourne; E J Triggs; V Heazlewood
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953
  1 in total

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