Literature DB >> 7329071

A model of ventricular fibrillation in the isolated rat heart.

B Woodward.   

Abstract

A simple technique is described for the induction of reversible ventricular fibrillation in the isolated rat heart. Fibrillation is induced by doubling the calcium chloride and halving the sodium chloride concentration of the perfusate. Fibrillation can be prevented by Class I antiarrhythmic drugs and verapamil.

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Year:  1981        PMID： 7329071     DOI： 10.1016/0160-5402(81)90111-x

Source DB:  PubMed          Journal:  J Pharmacol Methods        ISSN： 0160-5402


  3 in total

1.  The effects of ablations in the central nervous system on arrhythmias induced by coronary occlusion in the rat.

Authors:  M J Curtis; B A Macleod; M J Walker
Journal:  Br J Pharmacol       Date:  1985-11       Impact factor: 8.739

2.  Effects of halothane on arrhythmias induced by myocardial ischaemia.

Authors:  B A MacLeod; R McGroarty; R H Morton; M J Walker
Journal:  Can J Anaesth       Date:  1989-05       Impact factor: 5.063

3.  Antiarrhythmic actions of verapamil against ischaemic arrhythmias in the rat.

Authors:  M J Curtis; B A MacLeod; M J Walker
Journal:  Br J Pharmacol       Date:  1984-10       Impact factor: 8.739
  3 in total

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