Literature DB >> 732891

Homotaurine and muscimol mimic taurine and GABA effects on muscle tone and temperature regulation.

G P Sgaragli, V Carlà, M Magnani, A Giotti.   

Abstract

Taurine, homotaurine, GABA and muscimol, given intraventricularly to the conscious, unrestrained rabbit cause hypothermia and a reduction in skeletal muscle tone. Taurine and homotaurine desynchronize areas of the motor and limbic cortices, with GABA and muscimol synchronize both tracings and markedly depress the arousal reaction following external stimuli.

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Year:  1978        PMID： 732891     DOI： 10.1007/bf00508286

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  17 in total

Review 1.  The neuropharmacology of taurine.

Authors:  A Barbeau; N Inoue; Y Tsukada; R F Butterworth
Journal:  Life Sci       Date:  1975-09-01       Impact factor: 5.037

2.  Structure-activity determinants of pharmacological effects of amino acids and related compounds on central synapses.

Authors:  D P PURPURA; M GIRADO; T G SMITH; D A CALLAN; H GRUNDFEST
Journal:  J Neurochem       Date:  1959-01       Impact factor: 5.372

3.  GABA receptor binding with 3H (+) bicuculline-methiodide in rat CNS.

Authors:  H Mohler; T Okada
Journal:  Nature       Date:  1977-05-05       Impact factor: 49.962

4.  Inhibition of spinal neurons by glycine.

Authors:  D R Curtis; L Hösli; G A Johnston
Journal:  Nature       Date:  1967-09-30       Impact factor: 49.962

5.  Effects of amino acid compounds injected into cerebrospinal fluid spaces, on colonic temperature, arterial blood pressure and behaviour of the rat.

Authors:  G Sgaragli; F Pavan
Journal:  Neuropharmacology       Date:  1972-01       Impact factor: 5.250

6.  Rate of release of amino acids from the cerebral cortex in the cat as affected by brainstem and thalamic stimulation.

Authors:  H H Jasper; I Koyama
Journal:  Can J Physiol Pharmacol       Date:  1969-10       Impact factor: 2.273

7.  Thermoregulation around a new set-point' established in the monkey by altering the ratio of sodium to calcium ions within the hypothalamus.

Authors:  R D Myers; T L Yaksh
Journal:  J Physiol       Date:  1971-11       Impact factor: 5.182

8.  Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system.

Authors:  S R Zukin; A B Young; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1974-12       Impact factor: 11.205

9.  Influence of ambient temperature on the thermoregulatory responses to 5-hydroxytryptamine, noradrenaline and acetylcholine injected into the lateral cerebral ventricles of sheep, goats and rabbits.

Authors:  J Bligh; W H Cottle; M Maskrey
Journal:  J Physiol       Date:  1971-01       Impact factor: 5.182

10.  Intracerebroventricular taurine in rabbits: effects of normal body temperature, endotoxin fever and hyperthermia produced by PGE1 and amphetamine.

Authors:  W S Harris; J M Lipton
Journal:  J Physiol       Date:  1977-04       Impact factor: 5.182
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  6 in total

1.  Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injection of GABA, GABA(A) and GABA(B) agonists and antagonists.

Authors:  Maria Frosini; Massimo Valoti; Giampietro Sgaragli
Journal:  Br J Pharmacol       Date:  2003-12-08       Impact factor: 8.739

Review 2.  The organization and regulation of sleep. A review of the experimental evidence and a novel integrated model of the organizing and regulating apparatus.

Authors:  W P Koella
Journal:  Experientia       Date:  1984-04-15

3.  A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation.

Authors:  Maria Frosini; Casilde Sesti; Simona Saponara; Lorenzo Ricci; Massimo Valoti; Mitri Palmi; Fabrizio Machetti; Giampietro Sgaragli
Journal:  Br J Pharmacol       Date:  2003-06       Impact factor: 8.739

4.  The effects of systemically administered taurine and N-pivaloyltaurine on striatal extracellular dopamine and taurine in freely moving rats.

Authors:  J Salimäki; G Scriba; T P Piepponen; N Rautolahti; L Ahtee
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-07-26       Impact factor: 3.000

5.  Effect of pyrimidine nucleosides on body temperatures of man and rabbit in relation to pharmacokinetic data.

Authors:  G J Peters; C J van Groeningen; E Laurensse; I Kraal; A Leyva; J Lankelma; H M Pinedo
Journal:  Pharm Res       Date:  1987-04       Impact factor: 4.200

6.  Homotaurine: a GABAB antagonist in guinea-pig ileum.

Authors:  A Giotti; S Luzzi; S Spagnesi; L Zilletti
Journal:  Br J Pharmacol       Date:  1983-08       Impact factor: 8.739
  6 in total

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