| Literature DB >> 7328059 |
T Tsuruo, K Naganuma, H Iida, T Yamori, S Tsukagoshi, Y Sakurai.
Abstract
Bestatin, a chemically defined immunostimulant of low molecular weight, suppressed the gradually-occurring lymph node metastasis of P388 leukemia in CDF1 mice when administered i.p. at the doses of 1 approximately 30 micrograms/mouse. It could not, however, suppress the established large metastasis of P388 leukemia. Lymph node cells isolated from the mice given bestatin i.p. at 1 and 30 microgram/mouse showed cytostatic activity against P388 leukemic cells in vitro than those from the untreated mice.Entities:
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Year: 1981 PMID： 7328059 DOI： 10.7164/antibiotics.34.1206
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649