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Literature DB >> 7325937

Ethanol consumption: selective breeding in mice.

Abstract

From a foundation stock of HS/Ibg mice, mass selection has yielded high-ethanol acceptance (HEA) and low-ethanol acceptance (LEA) lines with distributions which show little overlap in the 10th generation. Divergence has been systematic and the estimate of the realized heritability after 10 generations of selective breeding is 0.21 +/- 0.04. Low to moderate correlations among three methods of measuring alcohol consumption, including the one on which selection was based, were shown in an F2 generation derived from C57BL/Ibg and C3H/Ibg mice.

Entities: Chemical Disease Species

Mesh：

Year: 1981 PMID： 7325937 DOI： 10.1007/bf01070812

Source DB: PubMed Journal: Behav Genet ISSN： 0001-8244 Impact factor: 2.805

11 in total

4. Accentuating effects of nicotine on ethanol response in mice with high genetic predisposition to ethanol-induced locomotor stimulation.

Authors: N R Gubner; C S McKinnon; C Reed; T J Phillips
Journal: Drug Alcohol Depend Date: 2012-07-12 Impact factor: 4.492

5. Localization of genes influencing ethanol-induced conditioned place preference and locomotor activity in BXD recombinant inbred mice.

Authors: C L Cunningham
Journal: Psychopharmacology (Berl) Date: 1995-07 Impact factor: 4.530

5 in total

Ethanol consumption: selective breeding in mice.

1. DEVELOPMENT OF ALCOHOL PREFERENCE IN BALB/C MICE.

2. Behavioral and physiological differences among rat strains specially selected for their alcohol consumption.

3. A comparison of the effects of alcohol on mice selectively bred for differences in ethanol sleep-time.

4. Replicated selection for body weight in mice.

5. Estimation of realised heritabilities from selection experiments. II. Selection in one direction.

6. Design and efficiency of selection experiments for estimating genetic parameters.

7. Heritability of alcohol preference in laboratory mice and rats.

8. Neurochemical and endocrinological studies of mice selectively bred for aggressiveness.

9. Ethanol preference in C57BL/6 and BALB/c mice at three ages and eight ethanol concentrations.

10. Ethanol selection by inbred mice. Mode of inheritance and the effect of age on the genetic system.

Review 1. Preclinical studies of alcohol binge drinking.

Review 2. Pharmacogenetic studies of alcohol self-administration and withdrawal.

3. Alcohol preference drinking in a mouse line selectively bred for high drinking in the dark.

4. Accentuating effects of nicotine on ethanol response in mice with high genetic predisposition to ethanol-induced locomotor stimulation.

5. Localization of genes influencing ethanol-induced conditioned place preference and locomotor activity in BXD recombinant inbred mice.