Literature DB >> 7320737

Antitumor agents. 49 tricin, kaempferol-3-O-beta-D-glucopyranoside and (+)-nortrachelogenin, antileukemic principles from Wikstroemia indica.

K H Lee, K Tagahara, H Suzuki, R Y Wu, M Haruna, I H Hall, H C Huang, K Ito, T Iida, J S Lai.   

Abstract

Bioassay-directed isolation of the antitumor extract of Wikstroemia indica (Thymelaeaceae) has led to the characterization of tricin, kaempferol-3-O-beta-D-glucopyranoside, and (+)-nortrachelogenin as the major antileukemic constituents. In addition, daphnoretin was identified as the potent antitumor principle in vivo against the Ehrlich ascites carcinoma growth in mice.

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Year:  1981        PMID: 7320737     DOI: 10.1021/np50017a003

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  8 in total

Review 1.  Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.

Authors:  Kuo-Hsiung Lee
Journal:  J Nat Prod       Date:  2010-03-26       Impact factor: 4.050

2.  Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen).

Authors:  Weihuan Huang; Xiaoli Zhang; Yifei Wang; Wencai Ye; Vincent Ec Ooi; Hau Yin Chung; Yaolan Li
Journal:  Chin Med       Date:  2010-06-21       Impact factor: 5.455

3.  Phyllostachys edulis compounds inhibit palmitic acid-induced monocyte chemoattractant protein 1 (MCP-1) production.

Authors:  Jason K Higa; Zhibin Liang; Philip G Williams; Jun Panee
Journal:  PLoS One       Date:  2012-09-18       Impact factor: 3.240

4.  A review on plant-derived natural products and their analogs with anti-tumor activity.

Authors:  K K Dholwani; A K Saluja; A R Gupta; D R Shah
Journal:  Indian J Pharmacol       Date:  2008-03       Impact factor: 1.200

5.  Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro.

Authors:  Hong-Fang Jiang; Zhuo Wu; Xue Bai; Yi Zhang; Ping He
Journal:  Oncol Lett       Date:  2014-06-30       Impact factor: 2.967

6.  Sikokianin D, a new C-3/C-3"-biflavanone from the roots of Wikstroemia indica.

Authors:  Jie Li; Lin-Yan Lu; Ling-Hui Zeng; Chong Zhang; Jia-Lei Hu; Xiang-Rong Li
Journal:  Molecules       Date:  2012-06-26       Impact factor: 4.411

7.  Suppression of DNCB-Induced Atopic Skin Lesions in Mice by Wikstroemia indica Extract.

Authors:  So-Yeon Lee; No-June Park; Jonghwan Jegal; Beom-Geun Jo; Sangho Choi; Sang Woo Lee; Md Salah Uddin; Su-Nam Kim; Min Hye Yang
Journal:  Nutrients       Date:  2020-01-08       Impact factor: 5.717

8.  Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo.

Authors:  H Cai; E A Hudson; P Mann; R D Verschoyle; P Greaves; M M Manson; W P Steward; A J Gescher
Journal:  Br J Cancer       Date:  2004-10-04       Impact factor: 7.640

  8 in total

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