| Literature DB >> 7320201 |
B L Zuraw, C H O'Hair, J H Vaughan, D A Mathison, J G Curd, D H Katz.
Abstract
A solid-phase radioimmunoassay was developed to detect immunoglobulin (Ig)E antibodies that bound to human IgG. IgE-rheumatoid factor activity was found in the serum of 18 of 20 patients with seropositive rheumatoid arthritis, 1 of 4 patients with seronegative rheumatoid arthritis, 3 of 32 patients with seronegative rheumatoid arthritis, 3 of 32 patients with asthma, and in 1 patient with hypocomplementemic vasculitis and iodide sensitivity. Immunopathologic implications of IgE-rheumatoid factor are discussed.Entities:
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Year: 1981 PMID： 7320201 PMCID： PMC370968 DOI： 10.1172/jci110418
Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808