Literature DB >> 7319401

Production and purification of Penicillium citreoviride toxin and its effect on TPP-dependent liver transketolase.

S C Datta, J J Ghosh.   

Abstract

The production isolation and purification of a yellow mycotoxin from Penicillium citreoviride NRRL 2579 in different culture media was described. When injected subcutaneously to albino rats it alters the kinetic pattern of transketolase (EC 2.2.1.1) in liver in vivo in a competitive manner. In vitro, the inhibition is noncompetitive in nature. However, addition of thiamine diphosphate (TPP) to the in vitro system relieved the inhibitory effect. These findings suggested a relationship between citreoviridin-induced beriberi and the probable antithiamine effect of the toxin.

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Year:  1981        PMID: 7319401     DOI: 10.1007/bf02927336

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN: 0015-5632            Impact factor:   2.099


  4 in total

1.  Regulation of hepatic transketolase activity by thiamin.

Authors:  M S Bamji
Journal:  Indian J Biochem Biophys       Date:  1973-12       Impact factor: 1.918

2.  Isolation and characterisation of a crystalline antithiamine factor from mustard seed, Brassica juncea.

Authors:  J Bhattacharya; D K Chaudhuri
Journal:  Biochim Biophys Acta       Date:  1974-03-20

3.  Isolation, partial characterisation of antithiamine factor present in rice-bran and its effect on TPP-transketolase system and Staphylococcus aureus.

Authors:  B Kumar; D K Chaudhuri
Journal:  Int J Vitam Nutr Res       Date:  1976       Impact factor: 1.784

4.  Antithiamine factor in cotton seed (Bombex malabericum)--its isolation and characterization.

Authors:  L Sarkar; D K Chaudhuri
Journal:  Int J Vitam Nutr Res       Date:  1976       Impact factor: 1.784

  4 in total
  4 in total

1.  Artificial antigen synthesis and the development of polyclonal antibody-based immunoassay for citreoviridin determination.

Authors:  Zhen Hong Zhuang; Shan Jin Que; Yue Ming Gao; Jun Yuan; Zhou Ye; Min Du; Guang Mei Lin; Li Cai Liu; Shi Hua Wang
Journal:  World J Microbiol Biotechnol       Date:  2013-07-31       Impact factor: 3.312

2.  Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin.

Authors:  Yi-Hsuan Wu; Chia-Wei Hu; Chih-Wei Chien; Yu-Ju Chen; Hsuan-Cheng Huang; Hsueh-Fen Juan
Journal:  PLoS One       Date:  2013-08-21       Impact factor: 3.240

3.  Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells.

Authors:  Juliana S Ruas; Edilene S Siqueira-Santos; Ignacio Amigo; Erika Rodrigues-Silva; Alicia J Kowaltowski; Roger F Castilho
Journal:  PLoS One       Date:  2016-03-07       Impact factor: 3.240

4.  Development and Characterization of Monoclonal Antibodies for the Mycotoxin Citreoviridin.

Authors:  Chris M Maragos; Yosuke Uchiyama; Naoki Kobayashi; Fumichika Kominato; Yoshiko Sugita-Konishi
Journal:  Toxins (Basel)       Date:  2019-10-30       Impact factor: 4.546

  4 in total

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