Literature DB >> 7318420

Symbolic programs for structural identification of linear pharmacokinetic systems.

R C Manaka, A Schumitzky, W Wolf.   

Abstract

Most parameter estimation techniques implicitly assume that it is possible to determine the parameters of the system uniquely if there were no noise in the output. In practice, this is not always the case. Whether or not this assumption is true for a given input-output experiment is the problem of structural identification. Two programs utilizing symbolic matrix calculus are presented which aid in solving this problem for linear systems. Pharmacokinetic examples are given.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7318420     DOI： 10.1016/0010-468x(81)90099-4

Source DB:  PubMed          Journal:  Comput Programs Biomed        ISSN： 0010-468X


  2 in total

1.  Idarubicin metabolism and pharmacokinetics after intravenous and oral administration in cancer patients: a crossover study.

Authors:  C M Camaggi; E Strocchi; P Carisi; A Martoni; A Tononi; M Guaraldi; M Strolin-Benedetti; C Efthymiopoulos; F Pannuti
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

2.  Epirubicin metabolism and pharmacokinetics after conventional- and high-dose intravenous administration: a cross-over study.

Authors:  C M Camaggi; E Strocchi; P Carisi; A Martoni; B Melotti; F Pannuti
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.