Abnormal visual-evoked potentials from eyes with optic nerve head drusen.

We evaluated 38 eyes (29 patients) with unilateral or bilateral optic nerve head drusen by means of visual field testing (static, tangent screen, and Goldmann perimetry), nerve fiber layer characterization (using red-free fundus photography), and flash visual-evoked potential testing. We found that 27 of 36 (75%) of the eyes with drusen had abnormal visual fields, 36 of 38 (94.7%) had abnormal nerve fiber layers, and 35 of 36 (97.2%) had abnormal visual-evoked potentials. The degree of abnormality on any one test did not reliably predict the results of either of the other two tests; however, there appeared to be an association between the visual-evoked potential aberrations and the retinal nerve layer deficits.