Literature DB >> 7315533

Fatal carbamazepine-associated hepatitis. Report of two cases.

G Hopen, I Nesthus, O D Laerum.   

Abstract

Fatal hepatitis associated with intake of carbamazepine occurred in two females, 37 and 23 years old. The former used carbamazepine to prevent alcohol withdrawal symptoms. She had also been treated with disulfiram. The latter had used the drug as the only medication for epilepsy. This report supports the view that carbamazepine may induce serious hepatic damage.

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Year:  1981        PMID: 7315533

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  5 in total

1.  The influence of long-term anticonvulsant therapy with diphenylhydantoin and carbamazepine on serum gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase.

Authors:  H G Aldenhövel
Journal:  Eur Arch Psychiatry Neurol Sci       Date:  1988

Review 2.  Carbamazepine overdose. Features of 33 cases.

Authors:  J F Seymour
Journal:  Drug Saf       Date:  1993-01       Impact factor: 5.606

3.  Carbamazepine-induced acute cholangitis.

Authors:  D Larrey; A Hadengue; D Pessayre; L Choudat; C DeGott; J P Benhamou
Journal:  Dig Dis Sci       Date:  1987-05       Impact factor: 3.199

Review 4.  Drug effects on the liver. An updated tabular compilation of drugs and drug-related hepatic diseases.

Authors:  J Ludwig; R Axelsen
Journal:  Dig Dis Sci       Date:  1983-07       Impact factor: 3.199

5.  Hepatoprotective and antioxidant activity of N-acetyl cysteine in carbamazepine-administered rats.

Authors:  Eswaran Maheswari; Ganesan Raja Lekshmi Saraswathy; Thakur Santhranii
Journal:  Indian J Pharmacol       Date:  2014 Mar-Apr       Impact factor: 1.200

  5 in total

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