Literature DB >> 731238

Effect of tinofedrine (Homburg D8955) on cerebral blood flow in multi-infarct dementia.

J Merory, G H Du Boulay, J Marshall, J Morris, R W Russell, L Symon, D J Thomas.   

Abstract

Tinofedrine, a new derivative of l-norephedrine, was examined for cerebral vasodilator activity in man. Ten patients with reduced cerebral blood flow (CBF) and multi-infarct dementia were given the drug intravenously. Cerebral blood flow increased significantly by 28% from a mean of 43.3 to 55.5 ml/100 g/min.

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Year:  1978        PMID: 731238      PMCID: PMC493190          DOI: 10.1136/jnnp.41.10.900

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  6 in total

1.  Regional cerebral blood flow estimated by 133-xenon inhalation.

Authors:  W D Obrist; H K Thompson; H S Wang; W E Wilkinson
Journal:  Stroke       Date:  1975 May-Jun       Impact factor: 7.914

2.  Use of venous blood for pH and carbon-dioxide studies especially in respiratory failure and during anaesthesia.

Authors:  D BROOKS; V WYNN
Journal:  Lancet       Date:  1959-01-31       Impact factor: 79.321

3.  Effect of nicergoline on cerebral blood flow.

Authors:  L D Iliff; G H Du Boulay; J Marshall; R W Russell; L Symon
Journal:  J Neurol Neurosurg Psychiatry       Date:  1977-08       Impact factor: 10.154

4.  Variations in mean cerebral blood flow under anesthesia at rest and during cortical activation.

Authors:  N I Palmer; D J Thomas; B B MacGillivray; G H Du Boulay; J Marshall; R R Russell; L Symon
Journal:  Stroke       Date:  1977 Mar-Apr       Impact factor: 7.914

5.  Cerebral vasodilator therapy in stroke.

Authors:  L C McHenry
Journal:  Stroke       Date:  1972 Nov-Dec       Impact factor: 7.914

6.  Local cerebral blood flow and vascular reactivity in a chronic stable stroke in baboons.

Authors:  L Symon; H A Crockard; N W Dorsch; N M Branston; J Juhasz
Journal:  Stroke       Date:  1975 Sep-Oct       Impact factor: 7.914

  6 in total

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