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Literature DB >> 7309237

Genetics of resistance to African trypanosomes: role of the H-2 locus in determining resistance to infection with Trypanosoma rhodesiense.

Abstract

Susceptibility and resistance to Trypanosoma rhodesiense infections in inbred and H-2 congenic strains of mice were studied. Mean survival times and patterns of parasitemia were examined. C3HeB/FeJ mice were highly susceptible; CBA/J, A/J, and BALB/cByJ mice displayed an intermediate level of susceptibility; whereas C57BL/10 mice were highly resistant. H-2 congenic strains with the BL/10 background resembled the BL/10 parental type, thereby suggesting that the major histocompatibility complex does not play a major role in regulating resistance and susceptibility to infection with T. rhodesiense.

Entities: Disease Gene Species

Mesh：

Substances：
H-2 Antigens

Year: 1981 PMID： 7309237 PMCID： PMC350897 DOI： 10.1128/iai.34.2.513-518.1981

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

18 in total

1. Trypanosoma cruzi: role of the immune response in the natural resistance of inbred strains of mice.

Authors: T Trischmann; H Tanowitz; M Wittner; B Bloom
Journal: Exp Parasitol Date: 1978-08 Impact factor: 2.011

2. Immunobiology of African trypanosomiasis.

Authors: J M Mansfield
Journal: Cell Immunol Date: 1978-08 Impact factor: 4.868

3. Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse.

Authors: D J Bradley; B A Taylor; J Blackwell; E P Evans; J Freeman
Journal: Clin Exp Immunol Date: 1979-07 Impact factor: 4.330

4. Trypanosoma congolense: inheritance of susceptibility to infection in inbred strains of mice.

Authors: W I Morrison; M Murray
Journal: Exp Parasitol Date: 1979-12 Impact factor: 2.011

5. Susceptibility of inbred strains of mice to Trypanosoma congolense: correlation with changes in spleen lymphocyte populations.

Authors: W I Morrison; G E Roelants; K S Mayor-Withey; M Murray
Journal: Clin Exp Immunol Date: 1978-04 Impact factor: 4.330

6. Neutralizing antibody in Rodent Malaria.

Authors: J Golenser; D T Spira; A Zuckerman
Journal: Trans R Soc Trop Med Hyg Date: 1975 Impact factor: 2.184

7. The role of genetics in Gross virus leukemogenesis.

Authors: F Lilly
Journal: Bibl Haematol Date: 1970

8. Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.

Authors: S M Lanham; D G Godfrey
Journal: Exp Parasitol Date: 1970-12 Impact factor: 2.011

9. Trypanosoma brucei: influence of host strain and parasite antigenic type on infections in mice.

Authors: C E Clayton
Journal: Exp Parasitol Date: 1978-04 Impact factor: 2.011

10. Regulation of Leishmania populations within the host. II. genetic control of acute susceptibility of mice to Leishmania donovani infection.

Authors: D J Bradley
Journal: Clin Exp Immunol Date: 1977-10 Impact factor: 4.330

9 in total

1. Biological variation among african trypanosomes: I. Clonal expression of virulence is not linked to the variant surface glycoprotein or the variant surface glycoprotein gene telomeric expression site.

Authors: Jill A Inverso; Timothy S Uphoff; Scott C Johnson; Donna M Paulnock; John M Mansfield
Journal: DNA Cell Biol Date: 2010-05 Impact factor: 3.311

2. Interleukin-4-dependent immunoglobulin G1 isotype switch in the presence of a polarized antigen-specific Th1-cell response to the trypanosome variant surface glycoprotein.

Authors: L R Schopf; H Filutowicz; X J Bi; J M Mansfield
Journal: Infect Immun Date: 1998-02 Impact factor: 3.441

Genetics of resistance to African trypanosomes: role of the H-2 locus in determining resistance to infection with Trypanosoma rhodesiense.

1. Trypanosoma cruzi: role of the immune response in the natural resistance of inbred strains of mice.

2. Immunobiology of African trypanosomiasis.

3. Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse.

4. Trypanosoma congolense: inheritance of susceptibility to infection in inbred strains of mice.

5. Susceptibility of inbred strains of mice to Trypanosoma congolense: correlation with changes in spleen lymphocyte populations.

6. Neutralizing antibody in Rodent Malaria.

7. The role of genetics in Gross virus leukemogenesis.

8. Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.

9. Trypanosoma brucei: influence of host strain and parasite antigenic type on infections in mice.

10. Regulation of Leishmania populations within the host. II. genetic control of acute susceptibility of mice to Leishmania donovani infection.

1. Biological variation among african trypanosomes: I. Clonal expression of virulence is not linked to the variant surface glycoprotein or the variant surface glycoprotein gene telomeric expression site.

2. Interleukin-4-dependent immunoglobulin G1 isotype switch in the presence of a polarized antigen-specific Th1-cell response to the trypanosome variant surface glycoprotein.

3. CpG oligodeoxynucleotide treatment enhances innate resistance and acquired immunity to African trypanosomes.

4. Trypanosoma rhodesiense: analysis of the genetic control of resistance among mice.

5. Antibody responses induced by immunization of inbred mice susceptible and resistant to African trypanosomes.

6. Trypanosoma rhodesiense infection in mice: sex dependence of resistance.

7. Effect of splenectomy on Trypanosoma lewisi infection in young rats.

8. Immune responses to Candida albicans in genetically distinct mice.

9. Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.