Literature DB >> 7306506

Complete amino acid sequences of bovine thymopoietins I, II, and III: closely homologous polypeptides.

T Audhya, D H Schlesinger, G Goldstein.   

Abstract

Complete amino acid sequences were determined for thymopoietins I and II (revision), isolated from bovine thymus, and for thymopoietin III, a newly identified polypeptide isolated from bovine spleen. Thymopoietin III (TP-III) is a 49 amino acid monomeric peptide that shows minor microheterogeneity at residue 34. The three thymopoietins have largely identical sequences yet some distinct differences, suggesting very recent evolution from a common gene. The complete amino acid sequences are (Formula: see text).

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Year:  1981        PMID: 7306506     DOI: 10.1021/bi00524a044

Source DB:  PubMed          Journal:  Biochemistry        ISSN: 0006-2960            Impact factor:   3.162


  20 in total

Review 1.  Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators.

Authors:  E L Ochoa; A Chattopadhyay; M G McNamee
Journal:  Cell Mol Neurobiol       Date:  1989-06       Impact factor: 5.046

Review 2.  Immunomodulation with thymopentin: in vitro studies.

Authors:  J Duchateau; K Bolla
Journal:  Med Oncol Tumor Pharmacother       Date:  1989

3.  Three distinct human thymopoietins are derived from alternatively spliced mRNAs.

Authors:  C A Harris; P J Andryuk; S Cline; H K Chan; A Natarajan; J J Siekierka; G Goldstein
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

4.  Isothermal and nonisothermal decomposition of thymopentin and its analogs in aqueous solution.

Authors:  M L Lee; S Stavchansky
Journal:  Pharm Res       Date:  1998-11       Impact factor: 4.200

Review 5.  Desensitization of central cholinergic mechanisms and neuroadaptation to nicotine.

Authors:  E L Ochoa; L Li; M G McNamee
Journal:  Mol Neurobiol       Date:  1990 Fall-Winter       Impact factor: 5.590

6.  Arg-Lys-Asp-Val-Tyr (thymopentin) accelerates the cholinergic-induced inactivation (desensitization) of reconstituted nicotinic receptor.

Authors:  E L Ochoa; S Medrano; M C de Carlin; A M Dilonardo
Journal:  Cell Mol Neurobiol       Date:  1988-09       Impact factor: 5.046

7.  Preparations of homeostatic thymus hormone consist predominantly of histones 2A and 2B and suggest additional histone functions.

Authors:  R Reichhart; M Zeppezauer; H Jörnvall
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

8.  The prothymocyte: cellular and molecular biology.

Authors:  E A Boyse
Journal:  Surv Immunol Res       Date:  1985

9.  Evidence for thymopoietin and thymopoietin/alpha-bungarotoxin/nicotinic receptors within the brain.

Authors:  M Quik; U Babu; T Audhya; G Goldstein
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

10.  Isolation and complete amino acid sequence of human thymopoietin and splenin.

Authors:  T Audhya; D H Schlesinger; G Goldstein
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

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