Literature DB >> 7306204

Identification of the metabolites of an antitumor tricyclic nucleoside (NSC-154020).

P D Schweinsberg, R G Smith, T L Loo.   

Abstract

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Year:  1981        PMID： 7306204     DOI： 10.1016/0006-2952(81)90577-3

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  7 in total

Review 1.  Inhibition of Akt with small molecules and biologics: historical perspective and current status of the patent landscape.

Authors:  Margrith E Mattmann; Sydney L Stoops; Craig W Lindsley
Journal:  Expert Opin Ther Pat       Date:  2011-06-02       Impact factor: 6.674

2.  Phase I clinical, pharmacokinetic, and pharmacodynamic study of the Akt-inhibitor triciribine phosphate monohydrate in patients with advanced hematologic malignancies.

Authors:  Deepa Sampath; Asifa Malik; William Plunkett; Billie Nowak; Betsy Williams; Michelle Burton; Srdan Verstovsek; Stefan Faderl; Guillermo Garcia-Manero; Alan F List; Said Sebti; Hagop M Kantarjian; Farhad Ravandi; Jeffrey E Lancet
Journal:  Leuk Res       Date:  2013-08-06       Impact factor: 3.156

3.  Structural mimicry of adenosine by the antitumor agents 4-methoxy- and 4-amino-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine as viewed by a molecular modeling method.

Authors:  A K Ghose; V N Viswanadhan; Y S Sanghvi; L D Nord; R C Willis; G R Revankar; R K Robins
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

Review 4.  Novel inhibitors of AKT: assessment of a different approach targeting the pleckstrin homology domain.

Authors:  E J Meuillet
Journal:  Curr Med Chem       Date:  2011       Impact factor: 4.530

Review 5.  The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.

Authors:  SubbaRao V Madhunapantula; Paul J Mosca; Gavin P Robertson
Journal:  Cancer Biol Ther       Date:  2011-12-15       Impact factor: 4.742

6.  The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane.

Authors:  N Berndt; H Yang; B Trinczek; S Betzi; Z Zhang; B Wu; N J Lawrence; M Pellecchia; E Schönbrunn; J Q Cheng; S M Sebti
Journal:  Cell Death Differ       Date:  2010-05-21       Impact factor: 15.828

7.  Triciribine increases LDLR expression and LDL uptake through stabilization of LDLR mRNA.

Authors:  Katrine Bjune; Lene Wierød; Soheil Naderi
Journal:  Sci Rep       Date:  2018-11-01       Impact factor: 4.379
  7 in total

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