Literature DB >> 7305279

delta-Aminolevulinate dehydrase: a new genetic polymorphism in man.

G Battistuzzi, R Petrucci, L Silvagni, F R Urbani, S Caiola.   

Abstract

A method has been developed for the electrophoretic and quantitative analyses of human red cell delta-aminolevulinate dehydrase (ALADH). The enzyme is under the control of an autosomal gene, with two common codominant alleles. ALADH1 and ALADH2, with frequencies of 0.89 and 0.11, respectively, in the Italian population. Mean phenotypic enzyme activities are nearly identical: 52,. 49 and 55 mIU/g Hb for ALADH 1, 2-1 and 2 phenotypes respectively.

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Year:  1981        PMID: 7305279     DOI: 10.1111/j.1469-1809.1981.tb00333.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  37 in total

1.  ALAD porphyria is a conformational disease.

Authors:  Eileen K Jaffe; Linda Stith
Journal:  Am J Hum Genet       Date:  2006-12-21       Impact factor: 11.025

2.  Genetic susceptibility to lead poisoning-A case report.

Authors:  Anita R Bijoor; T Venkatesh
Journal:  Indian J Clin Biochem       Date:  2007-09

3.  Polymorphism of delta-aminolevulinic acid dehydratase in lead-exposed workers.

Authors:  B Ziemsen; J Angerer; G Lehnert; H G Benkmann; H W Goedde
Journal:  Int Arch Occup Environ Health       Date:  1986       Impact factor: 3.015

4.  Ecogenetic studies in Atacameño Indians.

Authors:  H W Goedde; F Rothhammer; H G Benkmann; P Bogdanski
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

5.  Hereditary hepatic porphyria with delta aminolevulinate dehydrase deficiency: immunologic characterization of the non-catalytic enzyme.

Authors:  H de Verneuil; M Doss; N Brusco; C Beaumont; Y Nordmann
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

6.  The genetic polymorphism of delta-aminolevulinate dehydrase in Italy.

Authors:  R Petrucci; A Leonardi; G Battistuzzi
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

7.  Aminolevulinate dehydratase (E.C. 4.2.1.24): linkage analysis.

Authors:  A Amorim; J Kömpf; F Schunter; H Ritter
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

8.  Lack of association of delta-aminolevulinic acid dehydratase genotype with cytogenetic damage in lead workers.

Authors:  Fang-Yang Wu; Pao-Wen Chang; Chin-Ching Wu; Jim-Shoung Lai; Hsien-Wen Kuo
Journal:  Int Arch Occup Environ Health       Date:  2004-07-16       Impact factor: 3.015

9.  Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging Study.

Authors:  Pradeep Rajan; Karl T Kelsey; Joel D Schwartz; David C Bellinger; Jennifer Weuve; David Sparrow; Avron Spiro; Thomas J Smith; Huiling Nie; Howard Hu; Robert O Wright
Journal:  Am J Epidemiol       Date:  2007-09-06       Impact factor: 4.897

10.  Modification by ALAD of the association between blood lead and blood pressure in the U.S. population: results from the Third National Health and Nutrition Examination Survey.

Authors:  Franco Scinicariello; Ajay Yesupriya; Man-huei Chang; Bruce A Fowler
Journal:  Environ Health Perspect       Date:  2010-02       Impact factor: 9.031

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