Literature DB >> 7304609

Complement-fixing platelet autoantibodies in autoimmune thrombocytopenia.

W Kayser, C Meuller-Eckhardt, U Budde, R E Schmidt.   

Abstract

A 16-year-old male patient is described with chronic autoimmune thrombocytopenic purpura and, after two years, "warm" autoimmune hemolytic anemia (Evans syndrome) who transiently developed complement-fixing platelet autoantibodies. The autoreactivity of these antibodies was established by quantitative complement fixation as well as by absorption and elution studies using autologous platelets. We believe this to be the first documented case with this very rare and peculiar type of platelet autoantibody.

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Year:  1981        PMID: 7304609     DOI: 10.1002/ajh.2830110213

Source DB:  PubMed          Journal:  Am J Hematol        ISSN: 0361-8609            Impact factor:   10.047


  5 in total

1.  Recent trends in platelet antigen/antibody detection.

Authors:  C Mueller-Eckhardt; V Kiefel; S Santoso
Journal:  Blut       Date:  1989-07

2.  In vitro fixation of C3d and C5b-9 on platelets by human platelet reactive antibodies.

Authors:  V Kiefel; A Salama; C Mueller-Eckhardt
Journal:  Blut       Date:  1989-01

Review 3.  The role of complement in immune clearance of blood cells.

Authors:  U E Nydegger; M D Kazatchkine
Journal:  Springer Semin Immunopathol       Date:  1983

4.  Specific and nonspecific mechanisms of action of immunoglobulin G in therapy of idiopathic thrombocytopenic purpura (ITP).

Authors:  T W Jungi; P Imbach; S Barandun
Journal:  Blut       Date:  1984-06

5.  Possible mechanisms of intravenous immunoglobulin treatment in childhood idiopathic thrombocytopenic purpura (ITP).

Authors:  P Imbach; T W Jungi
Journal:  Blut       Date:  1983-03
  5 in total

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