Literature DB >> 7304548

Crohn's disease in the elderly.

P A Shapiro, M A Peppercorn, D A Antoniolo, N Joffe, H Goldman.   

Abstract

To determine the features of Crohn's disease in elderly patients we reviewed the charts, roentgenograms and pathology of patients with Crohn's disease admitted to our hospital from 1966 through 1979. Thirty-three patients (5.2% of the total) had the onset of symptoms and diagnosis made after age 60, including 18 (55%) with ileitis alone, 11 with colitis and four with ileocolitis. Six patients were seen, four with colitis and two with ileocolitis, with acute toxicity requiring early surgery. The clinical, radiographic and histologic characteristics of the disorder in older patients were otherwise similar to those described in younger patients. Differentiation of ischemic bowel disease and diverticulitis from Crohn's disease in such patients was difficult without reliance on histologic as well as clinical and roentgenographic features. Fifty-eight per cent of these older patients eventually required surgery, including 10 of 11 (91%) with colitis, two fo four with ileocolitis and seven of 18 (39%) with ileitis. The cumulative clinical recurrence rate, limited to patients with ileal disease, was 21% at nine years and 37% at 15 years.

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Mesh:

Year:  1981        PMID: 7304548

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  6 in total

Review 1.  Diverticular disease and chronic idiopathic inflammatory bowel disease: associations and masquerades.

Authors:  N A Shepherd
Journal:  Gut       Date:  1996-06       Impact factor: 23.059

Review 2.  Systematic Review and Meta-analysis: Phenotype and Clinical Outcomes of Older-onset Inflammatory Bowel Disease.

Authors:  Ashwin N Ananthakrishnan; Hai Yun Shi; Whitney Tang; Cindy C Y Law; Joseph J Y Sung; Francis K L Chan; Siew C Ng
Journal:  J Crohns Colitis       Date:  2016-02-29       Impact factor: 9.071

3.  Inflammatory bowel disease of the elderly: a wake-up call.

Authors:  Seymour Katz; Richard Feldstein
Journal:  Gastroenterol Hepatol (N Y)       Date:  2008-05

4.  Coexistent Crohn's disease and sigmoid diverticulosis.

Authors:  J McCue; M J Coppen; S A Rasbridge; M R Lock
Journal:  Postgrad Med J       Date:  1989-09       Impact factor: 2.401

5.  Crohn's disease in a 92-year-old male.

Authors:  T Narita; M Akiyama; H Ohnuma; K Matsuda
Journal:  J Gastroenterol       Date:  1996-02       Impact factor: 7.527

6.  Late-Onset Crohn's Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics.

Authors:  Dalin Li; Talin Haritunians; Carol Landers; Alka A Potdar; Shaohong Yang; Hailiang Huang; L Philip Schumm; Mark Daly; Stephan R Targan; Dermot P B McGovern
Journal:  Inflamm Bowel Dis       Date:  2018-10-12       Impact factor: 5.325

  6 in total

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