Literature DB >> 7304209

Effect of vasoactive intestinal polypeptide on cerebral blood flow in the goat.

J J Larsen, V Boeck, B Ottesen.   

Abstract

The effect of vasoactive intestinal polypeptide (VIP) on the cerebral blood flow was investigated in the goat. An electromagnetic flow probe was placed around the internal maxillary artery for continuous measurement of ipsilateral blood flow. Intraarterial injection of VIP resulted in a dose-dependent increase in the cerebral blood flow. The effect was not antagonized by any of the antagonists atropine, propranolol, phentolamine and naloxone administered intraarterially 1 min before VIP. It is discussed that VIP may play a physiological role in the local blood flow regulation in the CNS.

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Year:  1981        PMID： 7304209     DOI： 10.1111/j.1748-1716.1981.tb06765.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN： 0001-6772


  4 in total

Review 1.  Perivascular innervation of the cerebral circulation: involvement in the pathophysiology of subarachnoid hemorrhage.

Authors:  H Hara; L Edvinsson
Journal:  Neurosurg Rev       Date:  1987       Impact factor: 3.042

2.  Vasoactive intestinal polypeptide immunoreactive and cholinergic nerves in the whole mount preparation of the major cerebral arteries of the rat.

Authors:  S Kobayashi; K Kyoshima; J A Olschowka; D M Jacobowitz
Journal:  Histochemistry       Date:  1983

3.  Alterations in perivascular dilatory neuropeptides (CGRP, SP, VIP) in the external jugular vein and in the cerebrospinal fluid following subarachnoid haemorrhage in man.

Authors:  R Juul; H Hara; S E Gisvold; A O Brubakk; T A Fredriksen; G Waldemar; J F Schmidt; R Ekman; L Edvinsson
Journal:  Acta Neurochir (Wien)       Date:  1995       Impact factor: 2.216

4.  Distribution of vasoactive intestinal peptide-like immunoreactivity in the taste organs of teleost fish and frog.

Authors:  M Witt
Journal:  Histochem J       Date:  1995-02
  4 in total

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