Literature DB >> 7303042

Treatment program and comparison between anticoagulants and platelet aggregation inhibitors after transient ischemic attack.

A Burén, J Ygge.   

Abstract

Transient cerebral ischemic attacks (TIA) are an important warning symptom of threatening stroke from cerebral infarction (CI). A local treatment program aimed at identifying as many individuals with TIA as possible and treating them in a uniform manner is desirable. Platelet aggregation inhibitors with a combination of acetylsalicylic acid and dipyridamole (ASA + DP) has been compared with anticoagulants (AC). The average length of treatment was 24 months and all patients received the treatment for at least 6 months. Sixty patients received AC and 65 ASA + DP. Four patients in the ASA + DP group (6 percent) and 2 in the AC group (3.3 percent) sustained cerebral infarction. These figures are essentially lower than the expected incidence of 15--20 percent.

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Year:  1981        PMID: 7303042     DOI: 10.1161/01.str.12.5.578

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  6 in total

Review 1.  Transient ischemic attacks and stroke.

Authors:  T R Mirsen; V C Hachinski
Journal:  CMAJ       Date:  1988-06-15       Impact factor: 8.262

Review 2.  Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin.

Authors:  Els Llm De Schryver; Ale Algra; L Jaap Kappelle; Jan van Gijn; Peter J Koudstaal
Journal:  Cochrane Database Syst Rev       Date:  2012-09-12

3.  Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration.

Authors: 
Journal:  BMJ       Date:  1994-01-08

Review 4.  Clinical evaluation and management of transient ischemic attacks.

Authors:  J F Rothrock
Journal:  West J Med       Date:  1987-04

Review 5.  Risk of haemorrhage associated with long term anticoagulant therapy.

Authors:  M N Levine; G Raskob; J Hirsh
Journal:  Drugs       Date:  1985-11       Impact factor: 9.546

6.  A multiparametric index of platelet in vitro aggregation in cerebrovascular disease.

Authors:  P P Gazzaniga; P Ferroni; C Mina; F M Pulcinelli; P A Rizzo
Journal:  Ital J Neurol Sci       Date:  1987-12
  6 in total

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