| Literature DB >> 7302587 |
Y T Chen, D R Mattison, L Feigenbaum, H Fukui, J D Schulman.
Abstract
When pregnant rats were fed a 50 percent galactose diet there was a striking reduction in oocyte number in the offspring. The most prominent effects were noted after exposure to galactose during the premeiotic stages of oogenesis. Prenatal exposure to galactose or its metabolites may contribute to the premature ovarian failure characteristic of human galactosemia.Entities:
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Year: 1981 PMID： 7302587 DOI： 10.1126/science.7302587
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728