Literature DB >> 7300019

Mechanism of hypercholesterolemia in arteriolipidosis-prone rats (ALR).

Y Yamori, Y Kitamura, Y Nara, N Iritani.   

Abstract

The cholesterol metabolism of a newly established model for atherogenesis, named arteriolipidosis-prone rats (ALR), selected from spontaneously hypertensive rats (SHR), was investigated in comparison with a substrain of SHR (B) (nonarteriolipidosis-prone rats) and the normotensive control. Wistar-Kyoto (WK) rats. Serum cholesterol of ALR was significantly lower than that of WK. Uptake of labelled serum cholesterol by the isolated liver cells at 37 degrees C was higher in ALR than in WK. The data for SHR (B) fell in between these two. On the other hand, on feeding a cholesterol diet, serum cholesterol increased in the order WK, SHR (B) and ALR, with the highest being ALR. The absorption of cholesterol in ALR was about twice as great as in WK and SHR (B).

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Year:  1981        PMID： 7300019     DOI： 10.1253/jcj.45.1068

Source DB:  PubMed          Journal:  Jpn Circ J        ISSN： 0047-1828


  6 in total

1.  Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr.

Authors:  Kazuya Kitamori; Hisao Naito; Hazuki Tamada; Miya Kobayashi; Daisuke Miyazawa; Yuko Yasui; Kunihiro Sonoda; Satoru Tsuchikura; Naomi Yasui; Katsumi Ikeda; Takashi Moriya; Yukio Yamori; Tamie Nakajima
Journal:  Environ Health Prev Med       Date:  2011-08-19       Impact factor: 3.674

2.  A high cholesterol/cholate diet induced fatty liver in spontaneously hypertensive rats.

Authors:  K Ueno; H Okuyama
Journal:  Lipids       Date:  1986-08       Impact factor: 1.880

3.  Non-alcoholic steatohepatitis aggravates nitric oxide synthase inhibition-induced arteriosclerosis in SHRSP5/Dmcr rat model.

Authors:  Shogo Watanabe; Shota Kumazaki; Shusei Yamamoto; Ikumi Sato; Kazuya Kitamori; Mari Mori; Yukio Yamori; Satoshi Hirohata
Journal:  Int J Exp Pathol       Date:  2019-01-24       Impact factor: 1.925

4.  Efficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats.

Authors:  Hazuki Tamada; Hisao Naito; Kazuya Kitamori; Yumi Hayashi; Nozomi Yamagishi; Masashi Kato; Tamie Nakajima
Journal:  PLoS One       Date:  2016-01-04       Impact factor: 3.240

5.  A High-Fat and High-Cholesterol Diet Induces Cardiac Fibrosis, Vascular Endothelial, and Left Ventricular Diastolic Dysfunction in SHRSP5/Dmcr Rats.

Authors:  Shogo Watanabe; Shota Kumazaki; Katsuhiro Kusunoki; Terumi Inoue; Yui Maeda; Shinichi Usui; Ryoko Shinohata; Takashi Ohtsuki; Satoshi Hirohata; Shozo Kusachi; Kazuya Kitamori; Mari Mori; Yukio Yamori; Hisao Oka
Journal:  J Atheroscler Thromb       Date:  2017-11-22       Impact factor: 4.928

6.  L-citrulline inhibits body weight gain and hepatic fat accumulation by improving lipid metabolism in a rat nonalcoholic fatty liver disease model.

Authors:  Maya Kudo; Yoshie Yamagishi; Shiori Suguro; Masaaki Nishihara; Hisae Yoshitomi; Misa Hayashi; Ming Gao
Journal:  Food Sci Nutr       Date:  2021-07-16       Impact factor: 2.863
  6 in total

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