| Literature DB >> 7298223 |
K Ohuchi, S Yoshino, A Kurihara, H Yoshimura, M Ishiguro, S Kiso, S Tsurufuji.
Abstract
A strong delayed-type footpad reaction was established in mice using azobenzenearsonate-acetyl bovine serum albumin (ABA-AcBSA) as an antigen. Male ddY/S mice were sensitized by subcutaneous injection of 100 microliter of Freund's complete adjuvant - saline (1:1) emulsion containing 100 microgram of the antigen and challenged by subcutaneous injection of 2.5 microliter of Freund's incomplete adjuvant - saline (1:1) emulsion with 2.5 microgram antigen in the footpad on the 10th day after the sensitization. The analysis of the system which fulfilled criteria for delayed-type hypersensitivity with regard to kinetics, passive transfer and histology of the footpad reaction, and the effect of dexamethasone, indomethacin and quinacrine on the footpad reaction were described.Entities:
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Year: 1981 PMID： 7298223 DOI： 10.1159/000232848
Source DB: PubMed Journal: Int Arch Allergy Appl Immunol ISSN： 0020-5915