Literature DB >> 7298156

Variations in brain and heart acetylcholine content in rat: cervical dislocation vs guillotine technique.

B V Venkataraman, P S Shetty, T Joseph.   

Abstract

The stress induced in animals due to handling prior to sacrifice has been shown to produce changes in total acetylcholine (Ach) content of the brain and heart of adult rats. Two methods of killing the animals were compared viz. cervical dislocation and decapitation by a guillotine technique; the former method producing more handling stress than the latter. Ach levels were significantly lower both in brain and heart when the animals were killed by cervical dislocation.

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Year:  1981        PMID: 7298156

Source DB:  PubMed          Journal:  Indian J Physiol Pharmacol        ISSN: 0019-5499


  2 in total

Review 1.  Considerations for the use of anesthetics in neurotoxicity studies.

Authors:  Sumedha W Karmarkar; Kathleen M Bottum; Shelley A Tischkau
Journal:  Comp Med       Date:  2010-08       Impact factor: 0.982

2.  Brief anesthesia by isoflurane alters plasma corticosterone levels distinctly in male and female rats: Implications for tissue collection methods.

Authors:  Mandakh Bekhbat; Liana Merrill; Sean D Kelly; Vanessa K Lee; Gretchen N Neigh
Journal:  Behav Brain Res       Date:  2016-03-03       Impact factor: 3.332

  2 in total

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