Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Gene order in the major histocompatibility complex of the rat.

Literature DB >> 7298084

Gene order in the major histocompatibility complex of the rat.

H W Kunz, T J Gill, M Liebert, S M Katz.

Abstract

The loci in the major histocompatibility complex (MHC) of the rat which code for class I and class II antigens--RT1.A and RT1.B, respectively--have previously been separated by laboratory-derived recombinants and by observations in inbred and wild rats. Closely linked to the MHC is the growth and reproduction complex (Grc) which contains genes influencing body size (dw3) and fertility (ft). These phenotypic markers were used in this study to orient the A and B loci of the MHC. Two recombinants were used for mapping. The BIL(R1) animal is a recombinant between the MHC and Grc, and it carries the haplotype RT1.AlBlGrc+. The r10 animal is an intra-MHC recombinant, and it has the haplotype RT1.AnB1Grc. These recombinants were characterized serologically, by mixed lymphocyte reactivity, by immune responsiveness to poly (Glu52Lys33Tyr15) and by the presence of the dw-3 gene. The data demonstrate that the gene order of the loci is: dw-3--RT1.B--RT1.A.

Entities: Chemical Gene Species

Mesh：

Year: 1981 PMID： 7298084 DOI： 10.1007/bf00346018

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

21 in total

1. The major histocompatibility complex--comparison in the mouse, man, and the rat. A review.

Authors: T J Gill; D V Cramer; H W Kunz
Journal: Am J Pathol Date: 1978-03 Impact factor: 4.307

2. Comparison of the haplotypes of the major histocompatibility complex in the rat. III. Two difficult haplotypes: H-1h (Ag-B12) in the HW strain and Ag-B13 (H-1m) in the MNR/N strain.

Authors: O Stark; H W Kunz; T J Gill
Journal: J Immunogenet Date: 1978-08

3. Comparison of haplotypes of the major histocompatibility complex in the rat. II. Serological analysis of the haplotypes H-1a (Ag-B4), H-1d (Ag-B9) and H-1f (Ag-B10).

Authors: H W Kunz; O Stark; T J Gill
Journal: J Immunogenet Date: 1977-12

4. Comparison of haplotypes of the major histocompatibility complex in the rat. I. The Ag-B7 (H-1g) and Ag-B8 (H-1k) haplotypes.

Authors: O Stark; E Günther; H W Kunz; T J Gill
Journal: J Immunogenet Date: 1977-12

5. Quantitative micro-method for measuring antibody utilizing the bromoacetyl cellulose immunoadsorbant.

Authors: T J Gill; C F Bernard
Journal: Immunochemistry Date: 1969-07

6. The linkage of glyoxylase-I to the major histocompatibility complex in the rat.

Authors: V Stolc; H W Kunz; T J Gill
Journal: J Immunol Date: 1980-09 Impact factor: 5.422

7. The graft-versus-host reactivity in AG-B/MLR disparate strains of rats.

Authors: D V Cramer; B K Davis; J W Shonnard; T J Gill
Journal: Transplantation Date: 1977-06 Impact factor: 4.939

8. Comparison of the haplotypes of the major histocompatibility complex in the rat. IV. The six original Ag-B haplotypes.

Authors: O Stark; H W Kunz; T J Gill
Journal: J Immunogenet Date: 1979-04

9. Genetic and cellular factors in the immune response. I. Genetic control of the antibody response to poly Glu52 Lys33 Tyr15 in the inbred rat strains ACI and F344.

Authors: T J Gill; H W Kunz; D J Stechschulte; K F Austen
Journal: J Immunol Date: 1970-07 Impact factor: 5.422

10. Growth and reproduction complex in the rat. Genes linked to the major histocompatibility complex that affect development.

Authors: H W Kunz; T J Gill; B D Dixon; F H Taylor; D L Greiner
Journal: J Exp Med Date: 1980-12-01 Impact factor: 14.307

5 in total

5. A major histocompatibility complex-linked locus in the rat critically influences resistance to diethylnitrosamine carcinogenesis.

Authors: M F Melhem; H W Kunz; T J Gill
Journal: Proc Natl Acad Sci U S A Date: 1993-03-01 Impact factor: 11.205