Literature DB >> 729733

Effects of d1-methadone and morphine on developing chick embryo.

A Jakubovic, E G McGeer, P L McGeer.   

Abstract

Injections of methadone into the air space of fertile chicken eggs affected development of the embryo. Both methadone and morphine caused decreases in liver weight and brain protein, and morphine increased liver protein levels.

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Year:  1978        PMID： 729733     DOI： 10.1007/bf02034710

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  17 in total

1.  The effects of methadone on maternal-fetal interactions in the rat.

Authors:  J M Chandler; P W Robie; J C Schoolar; M M Desmond
Journal:  J Pharmacol Exp Ther       Date:  1975-03       Impact factor: 4.030

2.  Increased neonatal mortality in offspring of male rats treated with methadone or morphine before mating.

Authors:  D J Smith; J M Joffe
Journal:  Nature       Date:  1975-01-17       Impact factor: 49.962

3.  Infant of the addicted mother.

Authors:  C Zelson
Journal:  N Engl J Med       Date:  1973-06-28       Impact factor: 91.245

4.  Neonatal effects of heroin addiction and methadone-treated pregnancies. Preliminary report on 70 live births.

Authors:  M M Davis; B S Brown; S T Glendinning
Journal:  Proc Natl Conf Methadone Treat       Date:  1973

5.  Relative degree of tolerance to morphine sulfate and methadone hydrochloride in the rat and the interaction of dexamethasone.

Authors:  J H Brown; R L Garrett
Journal:  Arch Int Pharmacodyn Ther       Date:  1972-03

6.  Pregnancy in narcotics addicts treated by medical withdrawal. The methadone detoxification program.

Authors:  G Blinick; R C Wallach; E Jerez
Journal:  Am J Obstet Gynecol       Date:  1969-12-01       Impact factor: 8.661

7.  Effect of different methods of exposure to cyproterone acetate on mortality in chick embryos.

Authors:  W J Swartz
Journal:  Experientia       Date:  1977-09-15

8.  Comparative inhibition of biosynthetic processes in rat liver testicular cells by D-, L,-and DL-methadone.

Authors:  A Jakubovic; E G McGeer; P L McGeer
Journal:  Biochem Pharmacol       Date:  1978-01-01       Impact factor: 5.858

9.  Methadone during pregnancy in the rat: dose level effects on maternal and perinatal mortality and growth in the offspring.

Authors:  D E Hutchings; H F Hunt; J P Towey; T S Rosen; H S Gorinson
Journal:  J Pharmacol Exp Ther       Date:  1976-04       Impact factor: 4.030

10.  Development of a "blood-brain barrier" to methadone in the newborn rat.

Authors:  M A Peters
Journal:  J Pharmacol Exp Ther       Date:  1975-03       Impact factor: 4.030
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