Literature DB >> 7295513

Resistance to the cytocidal effects of adriamycin is an early phenotypic change induced during hepatocarcinogenesis.

B I Carr, B A Laishes.   

Abstract

Resistance to the cytocidal action of Adriamycin (ADR) was induced in rat hepatocytes by incorporation of the carcinogen 2-acetylaminofluorene (AAF) into the rat diet. Using a quantitative assay in primary monolayer culture, it was demonstrated that resistance to ADR is an early phenotypic change that is induced during chemical carcinogenesis in the rat, and appears to be stable.

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Year:  1981        PMID： 7295513      PMCID： PMC2010790          DOI： 10.1038/bjc.1981.227

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  13 in total

Review 1.  SENSITIVITY OF NORMAL AND NEOPLASTIC CELLS TO THE DAMAGING ACTION OF CARCINOGENIC SUBSTANCES: A REVIEW.

Authors:  J M VASILIEV; V I GUELSTEIN
Journal:  J Natl Cancer Inst       Date:  1963-11       Impact factor: 13.506

Review 2.  A CLONAL SELECTION THEORY OF CHEMICAL CARCINOGENESIS.

Authors:  R T PREHN
Journal:  J Natl Cancer Inst       Date:  1964-01       Impact factor: 13.506

3.  Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3'-methyl-4-dimethylaminoazobenzene.

Authors:  E FARBER
Journal:  Cancer Res       Date:  1956-02       Impact factor: 12.701

4.  [Histopathological study of the lesions produced by 2-acetylaminofluorene in different organs of the rat].

Authors:  J O LAWS; P MABILLE; R ROYER; G RUDALI
Journal:  Bull Assoc Fr Etud Cancer       Date:  1952

Review 5.  The role of antitumor antibiotics in current oncologic practice.

Authors:  H L Davis; D D von Hoff; J E Henney; M Rozencweig
Journal:  Cancer Chemother Pharmacol       Date:  1978       Impact factor: 3.333

Review 6.  The interaction of chemical carcinogens and cells in vitro.

Authors:  L Diamond
Journal:  Prog Exp Tumor Res       Date:  1969

7.  In vitro measurement of carcinogen-resistant liver cells during hepatocarcinogenesis.

Authors:  B A Laishes; E Roberts; E Farber
Journal:  Int J Cancer       Date:  1978-02-15       Impact factor: 7.396

8.  Therapy of local toxicities caused by extravasation of cancer chemotherapeutic drugs.

Authors:  R J Ignoffo; M A Friedman
Journal:  Cancer Treat Rev       Date:  1980-03       Impact factor: 12.111

9.  Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis.

Authors:  D B Solt; A Medline; E Farber
Journal:  Am J Pathol       Date:  1977-09       Impact factor: 4.307

10.  Tumorigenicity in vivo and induction of malignant transformation and mutagenesis in cell cultures by adriamycin and daunomycin.

Authors:  H Marquardt; F S Philips; S S Sternberg
Journal:  Cancer Res       Date:  1976-06       Impact factor: 12.701
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  2 in total

1.  Growth stimulation of primary rat hepatocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Authors:  D Wölfle; E Becker; C Schmutte
Journal:  Cell Biol Toxicol       Date:  1993 Jan-Mar       Impact factor: 6.691

2.  The British Association for Cancer Research, 23rd annual general meeting. Edinburgh 29--31 March 1982. Abstracts.

Authors: 
Journal:  Br J Cancer       Date:  1982-09       Impact factor: 7.640
  2 in total

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