Literature DB >> 7294882

Tolerance to corticoids? Guinea pig epithelium as an experimental system.

P Altmeyer, N Buhles.   

Abstract

The antiacanthogenic effect of topical applied steroids is well known and maybe exactly assessed and quantified by means of the test procedure described. A 0.1% clobetasol-17-propionate solution induces an antiacanthogenic effect of 27.5% after a 28-day treatment period. After 84 days, the skin further treated with the corticosteroid shows an antiacanthogenic effect of 23.7% and after 118 days of 39%. A steroid tolerance of epithelial layer on guinea pig skin cannot be derived from our results.

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Year:  1981        PMID： 7294882     DOI： 10.1007/bf00417382

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  14 in total

1.  Tachyphylaxis to the action of topically applied corticosteroids.

Authors:  A du Vivier; R B Stoughton
Journal:  Arch Dermatol       Date:  1975-05

2.  [ON THE EFFECT OF SOME ANTIECZEMA AGENTS ON THE NORMAL GUINEA PIG SKIN. I. TARS].

Authors:  K SALFELD; F ORTH
Journal:  Arch Klin Exp Dermatol       Date:  1965-02-12

3.  [Effect of hydrocortisone or prednisolone on experimental acanthosis].

Authors:  H J HEITE; F ROMMEL
Journal:  Dermatol Wochenschr       Date:  1958-09-13

4.  [Experimental acanthosis in guinea pigs].

Authors:  E BUJARD; R BRUN; W JADASSOHN
Journal:  Dermatologica       Date:  1957 Mar-Apr

5.  [Comparative animal experiments on epidermal hypoplasia induced by means of topical glucocorticoids].

Authors:  E G Weirich; J Longauer
Journal:  Z Hautkr       Date:  1974-02-01

6.  [The reactive epidermoplasia of guinea pig skin as a testing method for dermatologic agents].

Authors:  E G Weirich; C Schenk
Journal:  Dermatologica       Date:  1969

7.  [Histology of skin changes caused by external corticoid preparations].

Authors:  P Altmeyer
Journal:  Hautarzt       Date:  1977-02       Impact factor: 0.751

8.  [Reflexphotometric determinations of vasoconstriction after topical application of steroids. V. Vasoconstriction phaenomenon and tachyphylaxis after repeated steroid application (author's transl)].

Authors:  P Altmeyer; H Zaun
Journal:  Arch Dermatol Res       Date:  1976-03-10       Impact factor: 3.017

9.  Modification of experimental UV erythema by external steroids--a reflex photometric study.

Authors:  P Altmeyer
Journal:  Arch Dermatol Res       Date:  1977-04-27       Impact factor: 3.017

10.  Results of reflex photometric determinations of vasoconstriction after topical steroid application. Tachyphylaxis, relative and absolute refractory phase after single and multiple application of steroid.

Authors:  P Altmeyer; C Cremer
Journal:  Arch Dermatol Res       Date:  1977-01-31       Impact factor: 3.017
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