Literature DB >> 7294821

Shift of the acetylenic hydrogen during chemical and enzymatic oxidation of the biphenylacetylene triple bond.

P R Ortiz de Montellano, K L Kunze.   

Abstract

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Year:  1981        PMID： 7294821     DOI： 10.1016/0003-9861(81)90333-7

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


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  5 in total

Review 1.  Rearrangement reactions catalyzed by cytochrome P450s.

Authors:  Paul R Ortiz de Montellano; Sidney D Nelson
Journal:  Arch Biochem Biophys       Date:  2010-10-29       Impact factor: 4.013

2.  Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile.

Authors:  Xiaohai Li; Theodore M Kamenecka; Michael D Cameron
Journal:  Drug Metab Dispos       Date:  2010-04-09       Impact factor: 3.922

Review 3.  Acetylenes: cytochrome P450 oxidation and mechanism-based enzyme inactivation.

Authors:  Paul R Ortiz de Montellano
Journal:  Drug Metab Rev       Date:  2019-07-07       Impact factor: 4.518

4.  Covalent modification of Thr302 in cytochrome P450 2B1 by the mechanism-based inactivator 4-tert-butylphenylacetylene.

Authors:  Hsia-lien Lin; Haoming Zhang; Monica Jushchyshyn; Paul F Hollenberg
Journal:  J Pharmacol Exp Ther       Date:  2010-03-03       Impact factor: 4.030

5.  Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.

Authors:  Hsia-lien Lin; Haoming Zhang; Paul F Hollenberg
Journal:  J Pharmacol Exp Ther       Date:  2009-01-23       Impact factor: 4.030
  5 in total

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