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Literature DB >> 7294786

Isolation and characterization of two new trichothecenes from Fusarium sporotrichioides strain M-1-1.

Abstract

Two new trichothecenes were isolated along with T-2 toxin, neosolaniol, and HT-2 toxin from the culture filtrate of Fusarium sporotrichioides strain M-1-1. The structures of the new toxins were characterized to be 4 beta, 8 alpha-diacetoxy-12,13-epoxytrichothec-9-ene-3 alpha, 15-diol (designated NT-1) and 4 beta-acetoxy-12,13-epoxy-trichothec-9-ene-3 alpha,8 alpha,15-triol (designated NT-2).

Entities: Chemical Species

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Year: 1981 PMID： 7294786 PMCID： PMC244050 DOI： 10.1128/aem.42.3.541-543.1981

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

5 in total

1. Comparative toxicology of trichothec mycotoxins: inhibition of protein synthesis in animal cells.

Authors: Y Ueno; M Nakajima; K Sakai; K Ishii; N Sato
Journal: J Biochem Date: 1973-08 Impact factor: 3.387

2. Toxicological approaches to the metabolites of Fusaria. IV. Microbial survey on "bean-hulls poisoning of horses" with the isolation of toxic trichothecenes, neosolaniol and T-2 toxin of Fusarium solani M-1-1.

Authors: Y Ueno; K Ishii; K Sakai; S Kanaeda; H Tsunoda
Journal: Jpn J Exp Med Date: 1972-06

3. Inhibitory effects of mycotoxins on the protein synthesis in rabbit reticulocytes.

Authors: Y Ueno; M Hosoya; Y Ishikawa
Journal: J Biochem Date: 1969-09 Impact factor: 3.387

4. Environmental factors influencing the production of fusarenon-X, a cytotoxic mycotoxin of Fusarium nivale Fn 2B.

Authors: Y Ueno; Y Ishikawa; K Saito-Amakai; H Tsunoda
Journal: Chem Pharm Bull (Tokyo) Date: 1970-02 Impact factor: 1.645

5. Solaniol, a toxic metabolite of Fusarium solani.

Authors: K Ishii; K Sakai; Y Ueno; H Tsunoda; M Enomoto
Journal: Appl Microbiol Date: 1971-10

5 in total

6 in total

Isolation and characterization of two new trichothecenes from Fusarium sporotrichioides strain M-1-1.

1. Comparative toxicology of trichothec mycotoxins: inhibition of protein synthesis in animal cells.

2. Toxicological approaches to the metabolites of Fusaria. IV. Microbial survey on "bean-hulls poisoning of horses" with the isolation of toxic trichothecenes, neosolaniol and T-2 toxin of Fusarium solani M-1-1.

3. Inhibitory effects of mycotoxins on the protein synthesis in rabbit reticulocytes.

4. Environmental factors influencing the production of fusarenon-X, a cytotoxic mycotoxin of Fusarium nivale Fn 2B.

5. Solaniol, a toxic metabolite of Fusarium solani.

1. Trichothecene mycotoxins produced byFusarium sporotrichioides strain P-11.

2. Metabolism of T-2 toxin in Curtobacterium sp. strain 114-2.

3. HPLC of trichothecenes - Separation of neosolaniol, NT-1 toxin, and NT-2 toxin.

4. Isolation and characterization of a cytotoxic metabolite of Talaromyces bacillosporus.

Review 5. Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites.

6. The defense response in Arabidopsis thaliana against Fusarium sporotrichioides.