Literature DB >> 7288209

An outbreak of influenza B in an elderly population.

W N Hall, R A Goodman, G R Noble, A P Kendal, R S Steece.   

Abstract

An outbreak of influenza B occurred in an elderly population residing in a Minnesota nursing home between April 24 and May 21, 1979 and involved 129 (35.9%) of the 359 residents. Throat swabs from 11 and 19 acutely ill residents yielded influenza B virus similar to the B/Singapore/79 strain. Fourfold or greater increases in titer of complement-fixing or hemagglutination-inhibiting antibodies were detected in paired sera from 18 of the 19 persons affected and from three of 16 unaffected residents. Three hundred thirty-three (93%) of the 359 residents had received trivalent influenza virus vaccine in November 1978. The attack rate was age-specific and increased with age (z = 2.69; P = 0.007). Increasing susceptibility to influenza B with age in the elderly has not been previously demonstrated in this infrequently studied population. Increased risk for becoming ill was also found to be statistically associated with decreasing levels of care required and residence in closed wards and temporally associated with taking meals in the facility's dining areas.

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Year:  1981        PMID: 7288209     DOI: 10.1093/infdis/144.4.297

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  8 in total

1.  Increased sensitivity and reduced specificity of hemagglutination inhibition tests with ether-treated influenza B/Singapore/222/79.

Authors:  A P Kendal; T R Cate
Journal:  J Clin Microbiol       Date:  1983-10       Impact factor: 5.948

2.  The HI test modified by ether treatment in the sero-epidemiological surveillance of influenza B.

Authors:  R Pyhälä; M Kleemola; R Visakorpi
Journal:  J Hyg (Lond)       Date:  1985-06

3.  Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjects.

Authors:  R Gasparini; T Pozzi; E Montomoli; E Fragapane; F Senatore; M Minutello; A Podda
Journal:  Eur J Epidemiol       Date:  2001       Impact factor: 12.434

4.  Upper respiratory tract infection and serum antibody responses in nursing home patients.

Authors:  J C Arroyo; W Jordan; L Milligan
Journal:  Am J Infect Control       Date:  1988-08       Impact factor: 2.918

5.  Long-term care facilities: a cornucopia of viral pathogens.

Authors:  Ann R Falsey; Gerard E Dallal; Maria A Formica; Gloria G Andolina; Davidson H Hamer; Lynette L Leka; Simin Nikbin Meydani
Journal:  J Am Geriatr Soc       Date:  2008-06-28       Impact factor: 5.562

Review 6.  Vaccines for preventing influenza in the elderly.

Authors:  Vittorio Demicheli; Tom Jefferson; Carlo Di Pietrantonj; Eliana Ferroni; Sarah Thorning; Roger E Thomas; Alessandro Rivetti
Journal:  Cochrane Database Syst Rev       Date:  2018-02-01

Review 7.  Influenza outbreak control practices and the effectiveness of interventions in long-term care facilities: a systematic review.

Authors:  Kaitlin Rainwater-Lovett; Kevin Chun; Justin Lessler
Journal:  Influenza Other Respir Viruses       Date:  2013-11-07       Impact factor: 4.380

Review 8.  Viral respiratory illnesses.

Authors:  L J Anderson; P A Patriarca; J C Hierholzer; G R Noble
Journal:  Med Clin North Am       Date:  1983-09       Impact factor: 5.456

  8 in total

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