Literature DB >> 728801

In vivo voltammetry: monitoring of dopamine metabolites in CSF following release by electrical stimulation.

R M Wightman, E Strope, P Plotsky, R N Adams.   

Abstract

An in vivo electrochemical system which continuously records the concentration of metabolites of biogenic amines in small animal CSF is described. A small electrode, immersed in lateral ventricle CSF through a guide cannula, measures the amine metabolites by voltammetric oxidation. The detailed results of HVA release following electrical stimulation of the nigrostriatal pathway in rats are presented and compared with previous perfusion data. All the electrochemical results are verified by independent liquid chromatographic (chemical) analysis.

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Year:  1978        PMID： 728801     DOI： 10.1016/0006-8993(78)90109-9

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  4 in total

1.  Application of scanning electrochemical microscopy to biological samples.

Authors:  C Lee; J Kwak; A J Bard
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

2.  Correlation of 3-mercaptopropionic acid induced seizures and changes in striatal neurotransmitters monitored by microdialysis.

Authors:  Eric W Crick; Ivan Osorio; Mark Frei; Andrew P Mayer; Craig E Lunte
Journal:  Eur J Pharm Sci       Date:  2014-01-22       Impact factor: 4.384

3.  Probenecid sensitive pathway of elimination of dopamine and serotonin metabolites in CSF of the rat.

Authors:  J L Elghozi; E Mignot; K H Le Quan-Bui
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

4.  Homovanilic acid in Huntington's disease and Sydenham's chorea.

Authors:  L Cunha; C R Oliveira; M Diniz; R Amaral; A F Conçalves; J Pio-Abreu
Journal:  J Neurol Neurosurg Psychiatry       Date:  1981-03       Impact factor: 10.154
  4 in total

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