Literature DB >> 7286979

The chromosomal distribution of repetitive DNA sequences within the human beta globin gene cluster.

S Malcolm, P Barton, M A Ferguson-Smith.   

Abstract

The chromosomal distribution and degree of repetitiveness of the sequences within the human beta globin gene cluster has been studied by in situ hybridisation. A genomic recombinant, H beta G1, which contains 15.9 thousand base pairs (kb) of DNA inserted into lambda charon 4A, was used as a template for the [3H] complementary RNA used for hybridisation. The inserted DNA contains sequences 4.7 kb to the 5' side of the delta gene and continues through the delta and beta genes to a site 2.8 kb to the 3' side of the beta gene. Two highly repetitive sequences, which are distributed evenly over all the chromosomes, have been identified within this DNA. Another somewhat less repetitive sequence has been identified between the beta and delta genes.

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Year:  1981        PMID： 7286979     DOI： 10.1007/BF00281691

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  26 in total

1.  RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.

Authors:  C Duncan; P A Biro; P V Choudary; J T Elder; R R Wang; B G Forget; J K de Riel; S M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

Review 2.  Report of the committee on the genetic constitution of chromosomes 10, 11, 12, X, and Y.

Authors:  A de la Chapelle; O J Miller
Journal:  Cytogenet Cell Genet       Date:  1979

3.  Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli.

Authors:  M Bazaral; D R Helinski
Journal:  J Mol Biol       Date:  1968-09-14       Impact factor: 5.469

4.  Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.

Authors:  R J Britten; D E Kohne
Journal:  Science       Date:  1968-08-09       Impact factor: 47.728

5.  Molecular cloning and characterization of the human beta-like globin gene cluster.

Authors:  E F Fritsch; R M Lawn; T Maniatis
Journal:  Cell       Date:  1980-04       Impact factor: 41.582

6.  A ubiquitous family of repeated DNA sequences in the human genome.

Authors:  C M Houck; F P Rinehart; C W Schmid
Journal:  J Mol Biol       Date:  1979-08-15       Impact factor: 5.469

7.  Isolation and characterization of a 15-kilobase genomic sequence coding for part of the Pro alpha 2 chain of sheep type I collagen.

Authors:  C D Boyd; P Tolstoshev; M P Schafer; B C Trapnell; H C Coon; P J Kretschmer; A W Nienhuis; R G Crystal
Journal:  J Biol Chem       Date:  1980-04-10       Impact factor: 5.157

Review 8.  Heterochromatin and satellite DNA in man: properties and prospects.

Authors:  G L Miklos; B John
Journal:  Am J Hum Genet       Date:  1979-05       Impact factor: 11.025

9.  The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

Authors:  R M Lawn; E F Fritsch; R C Parker; G Blake; T Maniatis
Journal:  Cell       Date:  1978-12       Impact factor: 41.582

10.  The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions.

Authors:  J Lauer; C K Shen; T Maniatis
Journal:  Cell       Date:  1980-05       Impact factor: 41.582
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  1 in total

1.  Localization and characterization of members of a family of repetitive sequences in the goat beta globin locus.

Authors:  S E Spence; R M Young; K J Garner; J B Lingrel
Journal:  Nucleic Acids Res       Date:  1985-03-25       Impact factor: 16.971
  1 in total

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