Literature DB >> 728558

Recognition in adult patients of malformations induced by folic-acid antagonists.

E W Reich, R P Cox, M H Becker, N B Genieser, J G McCarthy, J M Converse.   

Abstract

Three patients are reported, two of whom had mothers who revealed ingestion of abortifacient drugs during pregnancy. All patients resemble one another and those described earlier with malformations that were probably either aminopterin- or methotrexate-induced. It is likely that Patients I and II have abnormalities associated with the teratogenic action of these folic-acid antagonists. The etiology of Patient III's defects remains uncertain.

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Year:  1978        PMID: 728558

Source DB:  PubMed          Journal:  Birth Defects Orig Artic Ser        ISSN: 0547-6844


  3 in total

1.  Fetal environment and congenital malformations.

Authors:  D N Singh
Journal:  Indian J Pediatr       Date:  1989 Sep-Oct       Impact factor: 1.967

2.  Medical abortion: what does the research tell us?

Authors:  L E Ferris; A S Basinski
Journal:  CMAJ       Date:  1996-01-15       Impact factor: 8.262

Review 3.  Stunted growth with more or less normal appearance.

Authors:  J R Bierich; H Enders; U Heinrich; R Huenges; M B Ranke; D Schoenberg
Journal:  Eur J Pediatr       Date:  1982-12       Impact factor: 3.183

  3 in total

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