Literature DB >> 7285558

Conversational SAAM--an interactive program for kinetic analysis of biological systems.

R C Boston, P C Greif, M Berman.   

Abstract

CONSAM is a conventional version of the kinetic modelling program SAAM. Adjoined to the model processing capability of SAAM, CONSAM additionally affords the user creation, inspection, and alteration capabilities in model manipulation, assessment, and development. To achieve this flexibility CONSAM incorporates a text editor, a solution-saving facility, a model image-saving facility and a graphics package. Command syntax and command logic checking together with command argument defaulting help make CONSAM easy to use. The use of CONSAM in modelling a non-linear drug response to a moderately complicated dosing strategy is presented.

Mesh:

Year:  1981        PMID: 7285558     DOI: 10.1016/0010-468x(81)90089-1

Source DB:  PubMed          Journal:  Comput Programs Biomed        ISSN: 0010-468X


  19 in total

1.  The role of metabolites in bioequivalency assessment. III. Highly variable drugs with linear kinetics and first-pass effect.

Authors:  A J Jackson
Journal:  Pharm Res       Date:  2000-11       Impact factor: 4.200

2.  The role of metabolites in bioequivalency assessment. I. Linear pharmacokinetics without first-pass effect.

Authors:  M L Chen; A J Jackson
Journal:  Pharm Res       Date:  1991-01       Impact factor: 4.200

Review 3.  Pharmacokinetic-pharmacodynamic modelling: history and perspectives.

Authors:  Chantal Csajka; Davide Verotta
Journal:  J Pharmacokinet Pharmacodyn       Date:  2006-01-11       Impact factor: 2.745

4.  Anorexic contribution to increased linoleate mobilization and oxidation in lymphoma-bearing mice.

Authors:  R Kannan; M Gan-Elepano; N Baker
Journal:  Lipids       Date:  1992-02       Impact factor: 1.880

5.  Successful radiotherapy of tumor in pretargeted mice by 188Re-radiolabeled phosphorodiamidate morpholino oligomer, a synthetic DNA analogue.

Authors:  Guozheng Liu; Shuping Dou; George Mardirossian; Jiang He; Surong Zhang; Xinrong Liu; Mary Rusckowski; Donald J Hnatowich
Journal:  Clin Cancer Res       Date:  2006-08-15       Impact factor: 12.531

6.  The assessment of bioavailability in the presence of nonlinear elimination.

Authors:  S D Hall; C B McAllister; G R Wilkinson
Journal:  J Pharmacokinet Biopharm       Date:  1988-06

7.  Clinical pharmacokinetics of ciclosporin A in bone marrow transplantation patients.

Authors:  P Bertault-Pérès; D Maraninchi; Y Carcassonne; J P Cano; J Barbet
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

8.  Turnover and fate of plasma free fatty acids in briefly-fasted lymphoma-bearing mice.

Authors:  N Baker; M Gan-Elepano; B A Guthrie; J F Mead
Journal:  Lipids       Date:  1989-12       Impact factor: 1.880

9.  Dynamic small-animal PET imaging of tumor proliferation with 3'-deoxy-3'-18F-fluorothymidine in a genetically engineered mouse model of high-grade gliomas.

Authors:  Michelle S Bradbury; Dolores Hambardzumyan; Pat B Zanzonico; Jazmin Schwartz; Shangde Cai; Eva M Burnazi; Valerie Longo; Steven M Larson; Eric C Holland
Journal:  J Nucl Med       Date:  2008-02-20       Impact factor: 10.057

10.  Increased glucose effectiveness in normoglycemic but insulin-resistant relatives of patients with non-insulin-dependent diabetes mellitus. A novel compensatory mechanism.

Authors:  J E Henriksen; F Alford; A Handberg; A Vaag; G M Ward; A Kalfas; H Beck-Nielsen
Journal:  J Clin Invest       Date:  1994-09       Impact factor: 14.808

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