Literature DB >> 7284984

Premature chromosome condensation in human large bowel cancer.

A Reichmann, B Levin.   

Abstract

Two patients with large bowel cancer are described in whose tumors the presence of cells with premature chromosome condensation (PCC) was encountered. The percentage of PCC In the tumors was 6.9 and 6.6%. We hypothesize that the near tetraploid chromosome number present in the tumor cells in both patients may be the product of fusion of two near diploid malignant cells. Also it is speculated that some colorectal tumors with chromosomes ranging from the hypotriploid to the hypotetraploid levels may be the result of cell fusion.

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Year:  1981        PMID： 7284984     DOI： 10.1016/0165-4608(81)90087-x

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  2 in total

1.  Secondary activation of c-abl may be related to translocation to the nucleolar organizer region in an in vitro cultured rat leukemia cell line (K3D).

Authors:  R Takahashi; K Mihara; S Maeda; T Yamaguchi; H L Chen; N Aoyama; S Murao; M Hatanaka; T Sugiyama
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

2.  Premature chromosome condensation--studies on human metastatic carcinoma cells.

Authors:  S Brüderlein; E Gebhart; E Siebert; M Augustus
Journal:  Hum Genet       Date:  1986-05       Impact factor: 4.132
  2 in total

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