Literature DB >> 7284686

Oral hyoscine butylbromide does not alter the pattern of small intestinal motor activity.

D G Thompson, D L Wingate.   

Abstract

1. Continuous recording of proximal jejunal motility of conscious healthy subjects was made following ingestion of 200 mg hyoscine butylbromide (ten times the recommended therapeutic dosage). 2. There was no detectable modification of fasting or postprandial motor activity, although the therapeutic potency of the standard intravenous dose was confirmed.

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Year:  1981        PMID: 7284686      PMCID: PMC2071644          DOI: 10.1111/j.1476-5381.1981.tb09149.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  6 in total

1.  Abnormal small-bowel motility demonstrated by radiotelemetry in a patient with irritable colon.

Authors:  D G Thompson; J M Laidlow; D L Wingate
Journal:  Lancet       Date:  1979 Dec 22-29       Impact factor: 79.321

2.  The effect of some oral anticholinergics on gastric emptying, pH and osmolarity in man.

Authors:  D Brömster; G Carlberger; G Lundh; J Möller; A Rosén
Journal:  Scand J Gastroenterol       Date:  1969       Impact factor: 2.423

3.  The gastrointestinal absorption and the excretion of H3-butylscopolamine (hyoscine butylbromide) in man.

Authors:  K Hellström; A Rosén; K Söderlund
Journal:  Scand J Gastroenterol       Date:  1970       Impact factor: 2.423

4.  Effects of hyoscine butylbromide on gut motility.

Authors:  J P Guignard; A Herxheimer; R M Greenwood
Journal:  Clin Pharmacol Ther       Date:  1968 Nov-Dec       Impact factor: 6.875

5.  Normal patterns of human upper small bowel motor activity recorded by prolonged radiotelemetry.

Authors:  D G Thompson; D L Wingate; L Archer; M J Benson; W J Green; R J Hardy
Journal:  Gut       Date:  1980-06       Impact factor: 23.059

6.  Treatment of irritable bowel syndrome with lorazepam, hyoscine butylbromide, and ispaghula husk.

Authors:  J A Ritchie; S C Truelove
Journal:  Br Med J       Date:  1979-02-10
  6 in total
  3 in total

1.  To precisely describe a profile of bizarre gastric emptying by breath testing.

Authors:  Masaki Sanaka; Hajime Anjiki; Takatsugu Yamamoto; Yasushi Kuyama
Journal:  Dig Dis Sci       Date:  2006-07       Impact factor: 3.199

2.  Effect of a tricyclic antidepressant on small intestinal motility in health and diarrhea-predominant irritable bowel syndrome.

Authors:  D A Gorard; G W Libby; M J Farthing
Journal:  Dig Dis Sci       Date:  1995-01       Impact factor: 3.199

Review 3.  Hyoscine butylbromide: a review of its use in the treatment of abdominal cramping and pain.

Authors:  Guido N Tytgat
Journal:  Drugs       Date:  2007       Impact factor: 9.546

  3 in total

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