[Transport of cytidinediphosphocholine in different biological models. I - Synthesis and characterization of (5 3H, Met 14 C) cytidinediphosphocholine].

In order to investigate the transport of CDP-choline across the biological membranes we have synthesized the double labeled CDP-choline. The (5 3H, methyl 14C) CDP-choline is synthesized by a crossed condensation of (5 3H) CMP and methyl 14C) p-choline using DCC as condensing agent. The product of the reaction is identified by chromatographics and spectroscopics methods.