Literature DB >> 7283749

Acute phalloidin poisoning in dogs.

U Mengs, W Trost.   

Abstract

The acute toxic effects of phalloidin, a toxin from the green deathcup, Amanita phalloides, were tested in dogs. No fatalities occurred following intravenous injection; however, the biochemical parameters GPT, GOT, alkaline phosphatase, and total bilirubin yielded pathological values. Histologically the liver parenchyma revealed hemorrhagic necrosis and peliosis-like changes with penetration of red blood cells into hepatocytes.

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Year:  1981        PMID： 7283749     DOI： 10.1007/BF00297076

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  10 in total

1.  [Recognition and treatment of mushroom poisoning].

Authors:  A E ALDER
Journal:  Dtsch Med Wochenschr       Date:  1961-06-09       Impact factor: 0.628

2.  Peliosis-like changes induced by phalloidin in the rat liver: a light and electron microscopic study.

Authors:  B Tuchweber; K Kovacs; J D Khandekar; B D Garg
Journal:  J Med       Date:  1973

Review 3.  The toxic peptides of Amanita phalloides.

Authors:  T Wieland
Journal:  Fortschr Chem Org Naturst       Date:  1967

4.  Effects of -amanitin on mouse and rat liver cell nuclei.

Authors:  V Marinozzi; L Fiume
Journal:  Exp Cell Res       Date:  1971-08       Impact factor: 3.905

5.  Antagonistic effects to phalloidin, alpha-amanitin and extracts of Amanita phalloides.

Authors:  G L Floersheim
Journal:  Agents Actions       Date:  1971-11

6.  Effects of penicillin and silymarin on liver enzymes and blood clotting factors in dogs given a boiled preparation of Amanita phalloides.

Authors:  G L Floersheim; M Eberhard; P Tschumi; F Duckert
Journal:  Toxicol Appl Pharmacol       Date:  1978-11       Impact factor: 4.219

7.  Prevention of silybin of phalloidin-induced acute hepatoxicity.

Authors:  B Tuchweber; R Sieck; W Trost
Journal:  Toxicol Appl Pharmacol       Date:  1979-11       Impact factor: 4.219

8.  [Amatoxins and mushroom poisoning].

Authors:  H Faulstich
Journal:  Naturwissenschaften       Date:  1979-08

Review 9.  Amatoxins, phallotoxins, phallolysin, and antamanide: the biologically active components of poisonous Amanita mushrooms.

Authors:  T Wieland; H Faulstich
Journal:  CRC Crit Rev Biochem       Date:  1978-12

10.  Phalloidin-induced cholestasis in the rat: relation to changes in microfilaments.

Authors:  M Dubin; M Maurice; G Feldmann; S Erlinger
Journal:  Gastroenterology       Date:  1978-09       Impact factor: 22.682
  10 in total
  1 in total

1.  Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.

Authors:  Yuan-Fu Lu; Jie Liu; Kai Connie Wu; Curtis D Klaassen
Journal:  Toxicol Lett       Date:  2014-10-01       Impact factor: 4.372
  1 in total

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