Phosphohexose isomerase polymorphism in the domestic cat.

Genetic variation of the enzyme phosphohexose isomerase (PHI) has been found in the erythrocytes of Australian domestic cats by horizontal starch gel electrophoresis at pH 8.2. Three complex patterns of isoenzymes, designated F, FS and S, were obtained migrating anodally. Limited family studies and the distribution of the three main phenotypes indicated that the polymorphism in controlled by two codominant autosomal alleles, PHIF and PHIS. Gene frequencies for PHIF and PHIS have been calculated as 0.036 and 0.964 respectively. Three additional variant forms have also been observed.