Literature DB >> 7283032

Distal splenorenal shunt. Hemodynamic advantage over total shunt and influence on clinical status, hepatic function and hypersplenism.

A Marni, C Trojsi, L Belli.   

Abstract

Clinical status, hepatic function and hypersplenism were investigated in 20 patients who underwent distal splenorenal shunt between January 1970 and June 1978. The operative morality rate was 5 percent, and encephalopathy of varying degrees affected 30 percent of the patients. There was no recurrence of bleeding, and the 3 to 5 year actuarial survival rate was 78 percent. Hypersplenism was significantly ameliorated in 17 patients (p less than 0.01). Serum glutamic improved and pyruvic transaminase significantly improved postoperatively and bilirubin significantly worsened, whereas other tests of liver function remained unchanged. Our results confirm the efficacy of this procedure in controlling recurrence of bleeding from esophageal varices. Moreover, severe hypersplenism is not an absolute contraindication to the shunt, which is preferable to total shunts since hepatopetal flow is preserved, thus avoiding early hepatic decompensation as demonstrated by the substantial stabilization of the liver function tests in the short run.

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Year:  1981        PMID: 7283032     DOI: 10.1016/0002-9610(81)90352-4

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  7 in total

1.  β-Blocker therapy ameliorates hypersplenism due to portal hypertension in children.

Authors:  Ujjal Poddar; Upender Shava; Surender Kumar Yachha; Jaya Agarwal; Sheo Kumar; Sanjay S Baijal; Anshu Srivastava
Journal:  Hepatol Int       Date:  2014-09-23       Impact factor: 6.047

2.  Red cell survival in patients with nonalcoholic liver cirrhosis before and after distal splenorenal shunt.

Authors:  M Nishiwaki; H Ashida; A Nishioka; J Utsunomiya
Journal:  J Gastroenterol       Date:  1997-06       Impact factor: 7.527

3.  The Effect of Transjugular Intrahepatic Portosystemic Shunt on Platelet Counts in Patients With Liver Cirrhosis.

Authors:  Omar I Massoud; Nizar N Zein
Journal:  Gastroenterol Hepatol (N Y)       Date:  2017-05

4.  Effect of transjugular intrahepatic portosystemic shunt on thrombocytopenia associated with cirrhosis.

Authors:  Z Karasu; A Gurakar; B Kerwin; S Hulagu; A Jazzar; R McFadden; B Nour; A Sebastian; F Cassidy; K Stokes; D H Van Thiel; H Wright
Journal:  Dig Dis Sci       Date:  2000-10       Impact factor: 3.199

5.  Loss of selectivity of Warren shunt in long-term observation.

Authors:  T Isomatsu
Journal:  Jpn J Surg       Date:  1983-05

6.  Portal thrombosis in cirrhotics. A retrospective analysis.

Authors:  L Belli; F Romani; C V Sansalone; P Aseni; G Rondinara
Journal:  Ann Surg       Date:  1986-03       Impact factor: 12.969

7.  Liver fibrosis is associated with decreased peripheral platelet count in patients with chronic hepatitis B and C.

Authors:  Zeki Karasu; Fatih Tekin; Galip Ersoz; Fulya Gunsar; Yucel Batur; Tankut Ilter; Ulus S Akarca
Journal:  Dig Dis Sci       Date:  2007-04-27       Impact factor: 3.487

  7 in total

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