Literature DB >> 7281182

Metabolism, cytotoxicity, and genotoxicity of the pyrrolizidine alkaloid senecionine in primary cultures of rat hepatocytes.

C E Green, J H Segall, J L Byard.   

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Year:  1981        PMID： 7281182     DOI： 10.1016/0041-008x(91)90221-y

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN： 0041-008X            Impact factor:   4.219


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  10 in total

1.  A simplified method for the culturing of primary adult rat and human hepatocytes as multicellular spheroids.

Authors:  A P Li; S M Colburn; D J Beck
Journal:  In Vitro Cell Dev Biol       Date:  1992 Sep-Oct

2.  Sulfation and glucuronidation of acetaminophen by cultured hepatocytes reproducing in vivo sex-differences in conjugation on Matrigel and type 1 collagen.

Authors:  R E Kane; J Tector; J J Brems; A Li; D Kaminski
Journal:  In Vitro Cell Dev Biol       Date:  1991-12

3.  Culturing of primary hepatocytes as entrapped aggregates in a packed bed bioreactor: a potential bioartificial liver.

Authors:  A P Li; G Barker; D Beck; S Colburn; R Monsell; C Pellegrin
Journal:  In Vitro Cell Dev Biol       Date:  1993-03

4.  Characterization of isolated Fe-loaded rat hepatocytes prepared by collagenase perfusion.

Authors:  C A Tyson; C E Green; S E LeValley; R J Stephens
Journal:  In Vitro       Date:  1982-11

5.  Effect of very long chain fatty acids on peroxisomal beta-oxidation in primary rat hepatocyte cultures.

Authors:  E N Christiansen; T J Gray; B G Lake
Journal:  Lipids       Date:  1985-12       Impact factor: 1.880

6.  Lipid peroxidation and cellular damage caused by the pyrrolizidine alkaloid senecionine, the alkenal trans-4-hydroxy-2-hexenal, and related alkenals.

Authors:  D S Griffin; H J Segall
Journal:  Cell Biol Toxicol       Date:  1987-12       Impact factor: 6.691

7.  Comparative metabolism and toxicity of chemical carcinogens in primary cultures of hepatocytes.

Authors:  J L Byard; K K Dougherty
Journal:  In Vitro Cell Dev Biol       Date:  1985-09

8.  Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies.

Authors:  Daniel G Stark; Patrick Williamson; Emma R Gayner; Stefania F Musolino; Ryan W F Kerr; James E Taylor; Alexandra M Z Slawin; Timothy J C O'Riordan; Stuart A Macgregor; Andrew D Smith
Journal:  Org Biomol Chem       Date:  2016-08-04       Impact factor: 3.876

9.  Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism.

Authors:  Xinmiao Yan; Hong Kang; Jun Feng; Yiyan Yang; Kailin Tang; Ruixin Zhu; Li Yang; Zhengtao Wang; Zhiwei Cao
Journal:  Int J Mol Sci       Date:  2016-03-07       Impact factor: 5.923

10.  Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells.

Authors:  Lukas Rutz; Lan Gao; Jan-Heiner Küpper; Dieter Schrenk
Journal:  Arch Toxicol       Date:  2020-09-10       Impact factor: 5.153
  10 in total

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