Literature DB >> 7280669

Progesterone regulation of the occupied form of nuclear estrogen receptor.

W C Okulicz, R W Evans, W W Leavitt.   

Abstract

Total concentrations of estrogen receptor in the uterine nuclear fraction are reduced rapidly after progesterone treatment of the proestrous hamster. Progesterone acts selectively on the occupied form of the nuclear estrogen receptor, with no effect on the concentration of an unoccupied form. This observation indicates that progesterone modulates the action of estrogen by controlling nuclear retention of the estrogen-receptor complex.

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Year:  1981        PMID： 7280669     DOI： 10.1126/science.7280669

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

Review 1.  Role of androgens and the androgen receptor in remodeling of spine synapses in limbic brain areas.

Authors:  Tibor Hajszan; Neil J MacLusky; Csaba Leranth
Journal:  Horm Behav       Date:  2007-12-31       Impact factor: 3.587

2.  Corpus luteum dysfunction and the epidemiology of breast cancer: a reconsideration.

Authors:  B M Sherman; R B Wallace; S G Korenman
Journal:  Breast Cancer Res Treat       Date:  1981       Impact factor: 4.872

3.  On the mechanism of estrogen receptor replenishment: recycling, resynthesis and/or processing.

Authors:  J A Kassis; J Gorski
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

4.  Structure-activity and structure-affinity relationships of 19-nor-progesterone derivatives in rat uterus.

Authors:  J Botella; I Duc; R Delansorne; J Paris; B Lahlou
Journal:  J Endocrinol Invest       Date:  1990-12       Impact factor: 4.256

5.  Contribution to the pathogenesis of dysmenorrhea.

Authors:  H P Zahradnik; M Breckwoldt
Journal:  Arch Gynecol       Date:  1984
  5 in total

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