Literature DB >> 727798

Hypomagnesaemic hypocalcaemia with hypokalaemia caused by treatment with high dose gentamicin.

C J Kelnar, W S Taor, D J Reynolds, D R Smith, B M Slavin, C G Brook.   

Abstract

A 12-year-old boy developed renal wasting of magnesium, calcium, and potassium, with secondary hypomagnesaemia, hypocalcaemia, and hypokalaaemia (without hyperaldosteronism) after treatment with 14 400 mg gentamicin over 4 months. Gentamicin should not be given for prolonged courses if less toxic antibiotics are suitable. If it used, plasma magnesium, calcium, and potassium levels should be monitored during and after treatment.

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Year:  1978        PMID: 727798      PMCID: PMC1545406          DOI: 10.1136/adc.53.10.817

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  7 in total

1.  Experimental aminoglycoside nephrotoxicity.

Authors:  F C Luft; V Patel; M N Yum; B Patel; S A Kleit
Journal:  J Lab Clin Med       Date:  1975-08

2.  Hypomagnesemic hypocalcemia secondary to renal magnesium wasting.

Authors:  R S Bar; H E Wilson; E L Mazzaferri
Journal:  Ann Intern Med       Date:  1975-05       Impact factor: 25.391

3.  Drug-induced secondary hyperaldosteronism in patients with pulmonary tuberculosis.

Authors:  A M Holmes; C M Hesling; T M Wilson
Journal:  Q J Med       Date:  1970-04

4.  Experimental human magnesium depletion.

Authors:  M E Shils
Journal:  Medicine (Baltimore)       Date:  1969-01       Impact factor: 1.889

5.  Gentamicin persistence in the body.

Authors:  J J Schentag; W J Jusko
Journal:  Lancet       Date:  1977-02-26       Impact factor: 79.321

6.  Letter: Prolonged excretion of gentamicin in a patient with umimpaired renal function.

Authors:  G Kahlmeter; G Kamme
Journal:  Lancet       Date:  1975-02-01       Impact factor: 79.321

7.  Functional hypoparathyroidism and parathyroid hormone end-organ resistance in human magnesium deficiency.

Authors:  R K Rude; S B Oldham; F R Singer
Journal:  Clin Endocrinol (Oxf)       Date:  1976-05       Impact factor: 3.478

  7 in total
  4 in total

Review 1.  Drug-induced hypomagnesaemia : scope and management.

Authors:  Jacob Atsmon; Eran Dolev
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

Review 2.  Drug-induced electrolyte abnormalities.

Authors:  E P Brass; W L Thompson
Journal:  Drugs       Date:  1982-09       Impact factor: 9.546

3.  Gentamicin Inhibits Ca2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor-Claudin-14 Pathway.

Authors:  Wouter H van Megen; Megan R Beggs; Sung-Wan An; Patrícia G Ferreira; Justin J Lee; Matthias T Wolf; R Todd Alexander; Henrik Dimke
Journal:  J Am Soc Nephrol       Date:  2022-01-12       Impact factor: 10.121

4.  Colistin-induced Bartter-like Syndrome: Ponder before Treatment!

Authors:  Anju Kumari; Poonam Gupta; Himanshu Verma; Ajay Kumar; Preeti Thakur; Kavish Sharma
Journal:  Indian J Crit Care Med       Date:  2022-02
  4 in total

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