Literature DB >> 7276559

Protection of neonatal mice against herpes simplex viral infection by human antibody and leukocytes from adult, but not neonatal humans.

S Kohl, L S Loo, L K Pickering.   

Abstract

Neither human immune globulin nor human mononuclear leukocytes (containing lymphocytes and monocytes) from herpes simplex virus (HSV) seronegative adult donors could protect infant C57BL/6 mice from a lethal HSV infection. In contrast, a combination of 5 X 10(6) leukocytes and a subneutralizing dose of antibody protected the mice. Leukocytes (5 X 10(6) or 1 X 10(7)) from neonatal humans and antibody could not mediate this protection. This is the first correlation between defective human neonatal leukocyte antibody-dependent cellular cytotoxicity (ADCC) in vitro and defective human neonate leukocyte-antibody protection against HSV infection in vivo in mice.

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Year:  1981        PMID： 7276559

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  7 in total

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2.  Analysis of the role of antibody-dependent cellular cytotoxic antibody activity in murine neonatal herpes simplex virus infection with antibodies to synthetic peptides of glycoprotein D and monoclonal antibodies to glycoprotein B.

Authors:  S Kohl; N C Strynadka; R S Hodges; L Pereira
Journal:  J Clin Invest       Date:  1990-07       Impact factor: 14.808

3.  Use of monoclonal antibodies for analysis of antibody-dependent immunity to ocular herpes simplex virus type 1 infection.

Authors:  J T Rector; R N Lausch; J E Oakes
Journal:  Infect Immun       Date:  1982-10       Impact factor: 3.441

4.  Ability of human cord blood lymphocytes to mediate antibody-dependent cellular cytotoxicity against influenza virus-infected cells.

Authors:  G Hashimoto; P F Wright; D T Karzon
Journal:  Infect Immun       Date:  1983-10       Impact factor: 3.441

5.  Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.

Authors:  Amy W Chung; Manu P Kumar; Kelly B Arnold; Wen Han Yu; Matthew K Schoen; Laura J Dunphy; Todd J Suscovich; Nicole Frahm; Caitlyn Linde; Alison E Mahan; Michelle Hoffner; Hendrik Streeck; Margaret E Ackerman; M Juliana McElrath; Hanneke Schuitemaker; Maria G Pau; Lindsey R Baden; Jerome H Kim; Nelson L Michael; Dan H Barouch; Douglas A Lauffenburger; Galit Alter
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Review 6.  Systems serology: profiling vaccine induced humoral immunity against HIV.

Authors:  Amy W Chung; Galit Alter
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Review 7.  Influenza and Antibody-Dependent Cellular Cytotoxicity.

Authors:  Tarra A Von Holle; M Anthony Moody
Journal:  Front Immunol       Date:  2019-06-25       Impact factor: 7.561
  7 in total

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