Literature DB >> 7275851

Studies on neplanocin A, new antitumor antibiotic. II. Structure determination.

M Hayashi, S Yaginuma, H Yoshioka, K Nakatsu.   

Abstract

The structure and stereochemistry of neplanocin A was determined on the basis of its spectral and chemical evidences as [1R-(la,2a,3b)]-3-(6-amino-9-yl)-5-(hydroxy-methyl)-4-cyclopentene-1,2-diol. For the final proof of the structure, X-ray crystallographic analysis of neplanocin A was carried out.

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Year:  1981        PMID： 7275851     DOI： 10.7164/antibiotics.34.675

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

1.  Carbocyclic pyrimidine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase.

Authors:  Sylvester L Mosley; Brian A Bakke; Joshua M Sadler; Naresh K Sunkara; Kathleen M Dorgan; Zhaohui Sunny Zhou; Katherine L Seley-Radtke
Journal:  Bioorg Med Chem       Date:  2006-08-10       Impact factor: 3.641

2.  A molecular model for the active site of S-adenosyl-L-homocysteine hydrolase.

Authors:  J C Yeh; R T Borchardt; A Vedani
Journal:  J Comput Aided Mol Des       Date:  1991-06       Impact factor: 3.686

3.  Antiviral and antimetabolic activities of neplanocins.

Authors:  E De Clercq
Journal:  Antimicrob Agents Chemother       Date:  1985-07       Impact factor: 5.191

Review 4.  The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold.

Authors:  Katherine L Seley-Radtke; Mary K Yates
Journal:  Antiviral Res       Date:  2018-04-10       Impact factor: 10.103

Review 5.  Novel insight into the regulatory roles of diverse RNA modifications: Re-defining the bridge between transcription and translation.

Authors:  Hanhan Shi; Peiwei Chai; Renbing Jia; Xianqun Fan
Journal:  Mol Cancer       Date:  2020-04-17       Impact factor: 27.401

6.  A novel route to a chiral building block for the preparation of cyclopentenyl carbocyclic nucleosides. Synthesis and anticancer activity of enantiomeric neplanocins A.

Authors:  Beata Łukasik; Maciej Mikina; Marian Mikołajczyk; Róża Pawłowska; Remigiusz Żurawiński
Journal:  RSC Adv       Date:  2020-08-27       Impact factor: 4.036

Review 7.  Analogues of Pyrimidine Nucleosides as Mycobacteria Growth Inhibitors.

Authors:  Liudmila A Alexandrova; Anastasia L Khandazhinskaya; Elena S Matyugina; Dmitriy A Makarov; Sergey N Kochetkov
Journal:  Microorganisms       Date:  2022-06-27

Review 8.  N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function.

Authors:  Yamei Niu; Xu Zhao; Yong-Sheng Wu; Ming-Ming Li; Xiu-Jie Wang; Yun-Gui Yang
Journal:  Genomics Proteomics Bioinformatics       Date:  2012-12-21       Impact factor: 7.691

9.  The first intermolecular interrupted imino-Nazarov reaction: expeditious access to carbocyclic nucleoside analogues.

Authors:  Ronny William; Wei Lin Leng; Siming Wang; Xue-Wei Liu
Journal:  Chem Sci       Date:  2015-10-27       Impact factor: 9.825
  9 in total

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